Neuropathy and myopathy can cause weakness during critical illness. To determine whether reduced excitability of peripheral nerves, rather than degeneration, is the mechanism underlying acute neuropathy in critically ill patients, we prospectively followed patients during the acute phase of critical illness and early recovery and assessed nerve conduction. During the period of early recovery fr...

Patients with chronic kidney disease (CKD) are at high risk for developing critical illness and for admission to intensive care units (ICU). 'Critically ill CKD patients' frequently develop an acute worsening of renal function (i.e. acute-on-chronic, AoC) that contributes to long-term kidney dysfunction, potentially leading to end-stage kidney disease (ESKD). An integrated multidisciplinary eff...

Abstract To explore the role of chronic liver disease (CLD) in COVID-19. A total 1439 consecutively hospitalized patients with COVID-19 from one large medical center United States March 16, 2020 to April 23, were retrospectively identified. Clinical characteristics and outcomes compared between without CLD. Postmortem examination 8 critically ill was performed. There no significant difference i...

Background: Red cell distribution width (RDW) is a routine laboratory measure that could be used as a predictor of mortality in critically ill patients. Identification of patients at risk for mortality early in the course of PICU admission is an important step in improving the outcome. We aimed to assess the use of RDW as an early biomarker for outcome in pediatric critical illnesses. Methods:...

RATIONALE Moving patients from low-performing hospitals to high-performing hospitals may improve patient outcomes. These transfers may be particularly important in critical care, where small relative improvements can yield substantial absolute changes in survival. OBJECTIVE To characterize the existing critical care network in terms of the pattern of transfers. METHODS In a retrospective co...

Hyperglycemia is commonly observed in critical illness. A landmark large randomized controlled trial (RCT) reported that the incidence of hyperglycemia (blood glucose concentration > 108 mg/dl) was as high as 97.2% in critically ill patients. During the past two decades, a number of RCTs and several meta-analyses and network meta-analyses have been conducted to determine the optimal target for ...

b a ckground:  nutritional care is of special importance in the control of the rate of mortality among intensive care unit (icu) patients. therefore, anthropometric and biochemical assessment are important among icu patients. we intend to report the anthropometric and biochemical indices, as well as the energy intake among icu patients in isfahan, iran. m ethods : this descriptive study was car...

T inten sive care unit (ICU) can be a stressful and intimidating environment for critically ill patients. Behavioral disturbances in critically ill patients may be detrimental to the safety of patients and the nurses caring for these patients. These disturbances may manifest as ICU delirium. The development of ICU delirium can lead to dire consequences, such as an increased risk of 6-month mort...

By definition, critical illness is any condition requiring support for failing vital functions, either with mechanical aids or with pharmacological agents (1). Concept of the modern critical care firstly appeared during the poliomyelitis epidemic of 1952 in Denmark. The increasing hospital admissions of patients with respiratory failure brought about the need for a distinct medical staff and de...