نتایج جستجو برای: croton tiglium l
تعداد نتایج: 619157 فیلتر نتایج به سال:
Carcinogenesis is a pathological process which may be mimicked in experimental models. The entire process may be subdivided into three steps: initiation, promotion and progression. The three steps of this model are routinely generated in mouse skin tissue, using the carcinogen 7,12 dimethylbenz [a]anthracene (DMBA) as an initiator, and cocarcinogens such as 12-O-tetradecanoylphorbol-13-acetate ...
In previous experiments by Berenblum and Shubik (4), tumors were induced in mice by a single application of a carcinogenic hydrocar bon, followed by repeated applications of noncarcinogenic croton oil. Friedewald and Rous (7) similarly showed that tumors may be induced in the rabbit by a suboptimal dose of carcinogen fol lowed by wound healing and applications of non specific agents, such as tu...
background: a growing body of preclinical data indicates that statins may possess antineoplastic properties however, some studies have raised the possibility that statins may also have carcinogenic potential. methods: an air pouch model was used for angiogenesis. single or multiple applications of croton oil on the back of swiss albino mice with or without initiation by dimethylbenz(a)antherace...
The focus of my research has been on understanding the initial events in phorbol ester action. The phorbol esters are natural products derived from Croton tiglium, the source of croton oil, and from other plants of the family Euphorbiaceae (1). The phorbol esters initially became the object of intense research interest on the basis of their potent activity as mouse skin tumor promoters (2). The...
In addition to the bound purine moieties of DNA and RNA, plants and animals contain a variety of other purine derivatives ranging in decreasing structural complexity from free nucleotides to simple substituted bases. Many of these compounds play important roles in metabolism and in its control and integration. Whereas most of the purine derivatives found in animal tissues also occur in plants, ...
Background: A growing body of preclinical data indicates that statins may possess antineoplastic properties however, some studies have raised the possibility that statins may also have carcinogenic potential. Methods: An air pouch model was used for angiogenesis. Single or multiple applications of croton oil on the back of Swiss albino mice with or without initiation by dimethylbenz(a)antherace...
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