نتایج جستجو برای: crypt depth
تعداد نتایج: 164930 فیلتر نتایج به سال:
The effect of 5-hydroxytryptamine (5-HT) on the crypt cell production rate in normal human duodenal mucosa cultured in vitro was studied using a stathmokinetic technique with crypt microdissection. The addition of 5-HT (2 mg/ml) to the culture medium significantly increased the crypt cell production rate (p < 000 1), suggesting that this amine may have a trophic effect on crypt cells in vitro. ...
High-dose ionizing radiation induces severe DNA damage in the epithelial stem cells in small intestinal crypts and causes gastrointestinal syndrome (GIS). Although the tumour suppressor p53 is a primary factor inducing death of crypt cells with DNA damage, its essential role in maintaining genome stability means inhibiting p53 to prevent GIS is not a viable strategy. Here we show that the innat...
The intestinal epithelial lining plays a central role in the digestion and absorption of nutrients, but exists in a harsh luminal environment that necessitates continual renewal. This renewal process involves epithelial cell proliferation in the crypt base and later cell migration from the crypt base to the luminal surface. This process is dependent on multi-potent progenitor cells, or stem cel...
Inorder to evaluate the effects of four sources of fiber (soy hulls, barley hull, rice husk and corn husks) each with two particle size (with 1 and 2- mm of geometric mean) on performance, nutrient digestibility, some blood parameters, small intestine morphology and secum bacteria in broiler chicken, 540 Ross308 broiler male chicks from 1 to 42 days were used in a completely randomized design w...
Ulcerative colitis is an inflammatory chronic disease primarily affecting the colonic mucosa. Neutrophils within epithelial structures, such as the crypt wall (cryptitis), or the crypt lumen and wall (crypt abscesses) or in association with crypt damage (crypt destruction) are helpful for the diagnosis. To assess ultrastructural changes of the colonic epithelium in patients with active UC with ...
Rectal mucosal proliferation has been promoted as an intermediate marker for risk of colorectal neoplasia. Proliferating cell nuclear antigen (PCNA) immunohistochemistry has become a standard method to measure cell proliferation. Whole-crypt dissection may provide a technically simpler method for determining proliferation within an entire crypt. We conducted a study to assess the reliability (r...
Teleost fish lack independent olfactory organs for odorant and pheromone detection. Instead, they have a single sensory epithelium with two populations of receptor neurons, ciliated and microvillous, that are conserved among vertebrates, and a unique receptor cell type named the olfactory crypt cell. Crypt cells were shown to be chemosensory neurons that project to specific areas in the olfacto...
An experiment was conducted under completely randomized design to study the effect of different levels of probiotic (500 and 1000g/feed for 1st phase (25 days) i.e. 35-60 days and at the levels of probiotic (250 and 500g/feed) as 2nd phase (50 days) i.e. 60-110 days. 90 rock partridges (35 day old) were randomly distributed into three treatments and five replicates (6 birds in each replicate) w...
Gut apical Na(+)-glucose cotransporter 1 (SGLT1) activity is high at the birth and during suckling, thus contributing substantially to neonatal glucose homeostasis. We hypothesize that neonates possess high SGLT1 maximal activity by expressing apical SGLT1 protein along the intestinal crypt-villus axis via unique control mechanisms. Kinetics of SGLT1 activity in apical membrane vesicles, prepar...
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