Gamna-Gandy bodies (siderotic nodules) represent organized foci of hemorrhage in the spleen that is caused by portal hypertension. Gamna-Gandy bodies contain hemosiderin, fibrous tissue, and calcium. Magnetic resonance imaging has been approved as the most sensitive imaging modality for the detection of these nodules due to their iron content. Computerized tomography and ultrasonography also he...

Achalasia cardia is a motility disorder of the esophagus characterized by failure of relaxation of the lower esophageal sphincter. Nitrates and calcium channel blockers, pneumatic dilatation, botulinum toxin injection and surgical myotomy have been described in literature as possible management options. We present a patient who presented with achalasia and was co-incidentally diagnosed to have ...

The molar ratio valine + leucine + isoleucine/phenylalanine + tyrosine was determined in the plasma of patients with liver disease of varying aetiology and severity and in an age and sex matched control group. In the control group of 58 subjects the mean ratio was 3.3 +/- 0.5 (ISD). The mean ratio was significantly lowered in groups of 25 patients with alcoholic cirrhosis (P less than 0.001), 2...

OBJECTIVE Refractory ascites is defined as a lack of response to high doses of diuretics or the development of diuretic related side effects, which compel the patient to discontinue the diuretic treatment. Current therapeutic strategies include repeated large-volume paracentesis and transjugular intrahepatic portosystemic shunts (TIPS). Peritoneovenous shunt (Denver shunt) should be considered ...

The survival of a recent series of 823 cirrhosis patients who were followed up for a mean of 48 months was analyzed. Cirrhosis was ascribed to alcohol (26%), hepatitis virus B (58%), hepatitis virus C (11%) or both (2%), or was cryptogenic (3%). Features of decompensation were observed in 51% of the patients at entry, and newly developed in 44% of compensated patients within 5 yr. The 5-yr surv...

Abstract Background Congenital hepatic fibrosis (CHF) is a rare disorder of the porto-biliary system occurring due to defective remodeling ductal architecture leading progressive portal tract. Though classically, CHF has been reported be associated with autosomal recessive polycystic kidney disease (ARPKD), there have only few reports associating dominant (ADPKD). Also, lack proper sequencing p...

Background: Hepatocellular carcinoma (HCC) is the most common primary malignant tumour of liver occurring in patients with underlying chronic disease high morbidity and mortality various clinical presentations. This study was conducted to analyse etiological profiles HCC tertiary care transplant centre.Methods: prospective cross-sectional department medical gastroenterology, government Stanley ...

Indian childhood cirrhosis (ICC), a disease considered to have been endemic in and unique to India has now been documented in children of non-Indian origin from other countries. More recently available findings from a large multicentre study sponsored by the Indian Council of Medical Research (ICMR) have dispelled some of the generally accepted notions and have established several new facts on ...

Introduction: Non Cirrhotic Portal Hypertension (NCPH) encompasses a wide range of disorders that are characterised by increased portal pressure with the absence cirrhosis liver. The classified anatomically based on site blood flow obstruction into prehepatic, hepatic and posthepatic causes. These numerous variable aetiological factors lack standardised diagnostic criteria, makes NCPH under-rec...