Here we examined the involvement of insulin-like growth factor 1 (IGF-1) on chemotherapy-induced cognitive impairment. Sixty-four ovariectomized female Sprague-Dawley rats were included in the study and given cyclophosphamide, methothrexate, and 5-fluorouracil (CMF) drug combination or saline (control). CMF was given once a week for 4 weeks. In one experiment, behavioral testing using the cued ...

In this paper, we investigated the statistical analysis of thermal conductivity of nanofluids containing of decorated Ag nanorods with Cu nanoparticles. For this purpose Ag-Cu hybrid is synthesized and characterized using transmission electron microscopy (TEM) and X-ray diffraction pattern (XRD). TEM image shows that Cu nanoparticles successfully decorate on the outer surface of Ag nanorods. Th...

This paper is presented to study the combustion process and emissions in a direct injection diesel engine. Computations are carried out using a three-dimensional model for flows, sprays, combustion and emissions in Diesel engines. Interactions between combustion and emissions with flow field are considered and it is shown that soot mass fraction increases at regions with low turbulence inten...

Chondromyxoid fibroma (CMF) is a rare benign cartilaginous tumor with a predilection for the bones of lower extremities and about one fourth of the tumors involve the foot.Radiologically, an eccentric lytic lesion with well defined margins is seen in the metaphysis of the bone. We hereby, report an 18 yr old young male who presented to Orthopedic Outpatient Department, JN Medical College, Aliga...

introduction: breast cancers are divided into at least 4 sub types on the basis of gene expression profiles and expression of receptors as measured by ihc (immunohistochemical). triple negative breast cancer (tnbc) is more chemosensitive yet, it is much harder to detect than other sub types. at present lack of highly effective therapeutic targets for tnbc, leaves standard chemotherapy, as the o...

The Highway Safety Manual [HSM, 2010] recommends safety evaluations be performed before implementing any roadway treatment to predict the expected safety consequences. Safety consequences can be measured using crash prediction models, Crash Modification Factor (CMFs), or both. This paper develops a CMF to show the expected impact of red-light cameras (RLCs) on safety at signalized intersections...

Aims. The expansion of hot ionized gas from an H ii region into a molecular cloud compresses the material and leads to the formation of dense continuous layers as well as pillars and globules in the interaction zone. Herschel imaging in the far-infrared (FIR) confirmed the presence of these dense features – potential sites of star-formation – at the edges of H ii regions. This feedback should a...

Purpose: The purpose of this study is to evaluate HER-2 and topoisomerase II (topo II ) as candidates for predicting the activity of anthracyclines in the adjuvant treatment of breast cancer patients. Experimental Design: In this study, we evaluated HER-2 and topo II gene aberrations by fluorescence in situ hybridization in a series of 430 primary breast cancer samples. Samples came from node-p...

BACKGROUND The optimal sequencing of chemotherapy and radiotherapy after breast surgery was largely studied but remains controversial. Concurrent chemo-radiotherapy is a valuable method for adjuvant treatment of breast cancer which is under ongoing research program in our hospital. We are evaluating the feasibility of the concomitant use of chemotherapy retrospectively. METHODS Two hundred fo...

BACKGROUND Previous analysis in a prospective, population-based cohort reported reduced weight gain in children fed extensively hydrolyzed casein (eHF-C) formula during the first year of life but showed no effect on growth between 1 and 6 y of life. No studies have been conducted in children up to the age of 10 y. OBJECTIVE The objective was to investigate potential differences in body mass i...