The Consensus Coding Sequence (CCDS) collaboration involves curators at multiple centers with a goal of producing a conservative set of high quality, protein-coding region annotations for the human and mouse reference genome assemblies. The CCDS data set reflects a 'gold standard' definition of best supported protein annotations, and corresponding genes, which pass a standard series of quality ...

The Rat Genome Database (RGD) is the premier repository of rat genomic, genetic and physiologic data. Converting data from free text in the scientific literature to a structured format is one of the main tasks of all model organism databases. RGD spends considerable effort manually curating gene, Quantitative Trait Locus (QTL) and strain information. The rapidly growing volume of biomedical lit...

During the last decade, national and international attention has been increasingly focused on issues of research data management and access to publicly funded research data. The pressure brought to bear on researchers to improve their data management and data sharing practice has come from research funders seeking to add value to expensive research and solve crossdisciplinary grand challenges; ...

SUMMARY Social media such as microblogs have become so pervasive such that it is now possible to use them as sensors for real-world events and memes. While much recent research has focused on developing automatic methods for filtering and summarizing these data streams, we explore a different trend called social curation. In contrast to automatic methods, social curation is characterized as a h...

Can we use programs for automated or semi-automated information extraction from scientific texts as practical alternatives to professional curation? I show that error rates of current information extraction programs are too high to replace professional curation today. Furthermore, current IEP programs extract single narrow slivers of information, such as individual protein interactions; they ca...

Telehealth monitoring data is now being collected across large populations of patients with chronic diseases such as stroke, hypertension, COPD and dementia. These large, complex and heterogeneous datasets, including distributed sensor and mobile datasets, present real opportunities for knowledge discovery and re-use, however they also generate new challenges for curation. This paper uses quali...

UNLABELLED Gene function curation of the literature with Gene Ontology (GO) concepts is one particularly time-consuming task in genomics, and the help from bioinformatics is highly requested to keep up with the flow of publications. In 2004, the first BioCreative challenge already designed a task of automatic GO concepts assignment from a full text. At this time, results were judged far from re...

The Research Data Alliance (RDA) Metadata Standards Directory Working Group (MSDWG) is building a directory of descriptive, discipline-specific metadata standards. The purpose of the directory is to promote the discovery, access and use of such standards, thereby improving the state of research data interoperability and reducing duplicative standards development work. This work builds upon the ...

Digital curation is a new term that encompasses ideas from established disciplines: it defines a set of activities to manage and improve the transfer of the increasing volume of data products from producers of digital scientific and academic data to consumers, both now and in the future. Research topics in this new area are in a formative stage, but a variety of work that can serve to advance t...