Demethoxycurcumin, isolated from the rhizomes of Curcuma longa, was found to possess antitubercular activity against Mycobacterium tuberculosis H (37)Rv strain at 200 microg/mL. Derivatisation of this active principle yielded a potent agent 6, exhibiting considerable activity with a minimum inhibitory concentration (MIC) value of 7.8 microg/mL. H (37)Rv:Mycobacterium tuberculosis H (37)Rv strai...

In a search for plant extracts with potent antimicrobial activity, turmeric (Curcuma longa) was extracted to get volatile oil and total curcuminoids .Further total curcuminoids portion was isolated by column chromatography to get curcumin , bisdemethoxycurcumin and demethoxycurcumin. The isolated curcuminoids were identified and characterized by melting point, thin layer chromatography, infra r...

In this paper, detailed meiotic analysis was investigated in seven species of Curcuma (Linnaeus, 1753) which can contribute significantly to our understanding about species inter-relationship, speciation and evolution. The species were divided into two groups viz., Group I having 2n = 42 (C. comosa Roxburgh, 1810, C. haritha Mangaly & M.Sabu, 1993, C. mangga Valeton & Zijp, 1917, and C. motana ...

The efficiency of turmeric fractions, such as petroleum ether, chloroform, benzene, methanol and aqueous were evaluated for their inhibitory effect on clinical standard strains pathogenic bacteria fungus. methanolic fraction Curcuma longa rhizome had high potential to inhibit some i.e. S. aureus a greater degree than other fractions longa. In our study the results show that different (petroleum...

Turmeric is a spice derived from the rhizomes of Curcuma longa, which is a member of the ginger family (Zingiberaceae). Rhizomes are horizontal underground stems that send out shoots as well as roots. The bright yellow color of turmeric comes mainly from fat-soluble, polyphenolic pigments known as curcuminoids. Curcumin, the principal curcuminoid found in turmeric, is generally considered its m...

To identify plants with bioactive potential for skin care, methanol extracts of 56 plant parts from 47 medical and edible plants cultivated in Okinawa were tested for their proliferative effects on NB1RGB skin fibroblast cells. Extracts from six plants, Bischofia javanica, Colocasia esculenta, Melaleuca alternifolia, Piper angustifolia, Jasminum sambac, and Curcuma longa, showed higher NB1RGB c...

Curcumin, an active constituent of Curcuma longa, is responsible for the for anticarcinogenic activities which is mediated through multiple mechanisms. Curcumin affects the major transcription factors such as nuclear factor k-light chain-enhancer of activated B cell(NF-kB) and activator protein-1 (AP-1).These factors regulate inflammation and are responsible for cell proliferation, differentiat...

Shamima Akhtar SHARMIN, Mohammad Jahangir ALAM, Md. Mominul Islam SHEIKH, Rashed ZAMAN, Muhammad KHALEKUZZAMAN, Sanjoy Chandra MONDAL, Mohammad Anwarul HAQUE, Mohammad Firoz ALAM, Iftekhar ALAM* Division of Applied Life Sciences (BK21 Program), College of Agriculture and Life Science, Gyeongsang National University, Jinju, Republic of Korea Department of Bioscience (Integrated Bioscience Sectio...

This study focused on maximizing the extraction yield of total phenolics and flavonoids from Curcuma Zedoaria leaves as a function of time (80-120 min), temperature (60-80 °C) and ethanol concentration (70-90 v/v%). The data were subjected to response surface methodology (RSM) and the results showed that the polynomial equations for all models were significant, did not show lack of fit, and pre...