A cytogenetic characterization, including heterochromatin content, and the analysis of the location of rDNA genes, was performed in Largus fasciatus Blanchard, 1843 and L. rufipennis Laporte, 1832. Mitotic and meiotic analyses revealed the same diploid chromosome number 2n = 12 + X0/XX (male/female). Heterochromatin content, very scarce in both species, revealed C-blocks at both ends of autosom...

appears that certain combinations of mutant alleles at the white locus in the chromosome of Drosophila melanogaster give rise at meiosis to unequal exchanges. These exchanges result in complementary deficiency and duplication chromatids. Furthermore, with a given combination of alleles, the exchanges seem to involve specific regions within or close to the white locus, so that the resulting defi...

Metastatic breast cancer (MBC) remains in most cases an incurable disease with genetic complexity and heterogeneity. Improvements classification management have been introduced, addition to the development of endocrine anti-HER2 targeted therapies. Currently, efforts are being made delineate best approach for genomic landscape MBC and, as result, molecular therapeutic targets. Here, we highligh...

Vibrational spectroscopy, based on either infrared absorption or Raman scattering, has attracted increasing attention for biomedical applications. Proof of concept explorations diagnosis oral potentially malignant disorders and cancer are reviewed, recent advances critically appraised. Specific examples applications microspectroscopy analysis histological, cytological saliva samples presented i...

Cytological evaluation of cutaneous and mucosal tumors presents a diagnostic challenge. Preoperative diagnosis is of great importance for the right choice of treatment, in the maxillofacial surgery. The recognition of the lesions may be accomplished by clinical, radiological, cytological and histopathological examination. Cytological examination of cutaneous tumors is not as yet a well recogniz...