Although dietary lipids have been implicated in colon cancer causation, the underlying mechanisms are not known. This paper indicates that when bacteria obtained from normal human feces are incubated with 14C-labeled phosphatidylcholine there is appreciable production of diacylglycerol (DAG), monoacylglycerol, and free fatty acid. Curiously, the production of DAG and monoacylglycerol, but not f...

Induction of neurite outgrowth by treating pheochromocytoma cells (PC12 cells) with nerve growth factor (NGF) is associated with major increases in cellular levels of diacylglycerol (DAG), an essential and probably limiting precursor in phosphatidylcholine (PC) and phosphatidylethanolamine (PE) syntheses. To identify the sources of this DAG we examined the effects of NGF treatment on the conver...

Diacylglycerol (DAG) oil is becoming quite well known for its beneficial effects on obesity and weight related disorders as they are digested and metabolized in a different way, which significantly reduces body weight. The present study was conducted to evaluate the nutritional effect of rice bran oil (RBO) and DAG-rich rice bran oil on rat model. DAG-rich RBO (46.10% DAG) was prepared in the l...

Insulin stimulated protein synthesis in L6 myoblasts but did not increase the labelling of DAG or the release of phosphocholine from phosphatidylcholine. The DAG lipase inhibitor, RHC 80267, more than doubled the amount of label appearing in DAG but did not stimulate protein synthesis. Even in the presence of the DAG lipase inhibitor insulin failed to have any effect on DAG labelling, and conve...

The capsaicin receptor, known as transient receptor potential channel vanilloid subtype 1 (TRPV1), is activated by a wide range of noxious stimulants and putative ligands such as capsaicin, heat, pH, anandamide, and phosphorylation by protein kinase C (PKC). However, the identity of endogenous activators for TRPV1 under physiological condition is still debated. Here, we report that diacylglycer...

We introduce directed acyclic graph (DAG) games, a generalization of standard tree games, to study cost sharing on networks. This structure has not been previously analyzed from a cooperative game theoretic perspective. Every monotonic and subadditive cost game – including monotonic minimum cost spanning tree games – can be modeled as a DAG-game. We provide an efficiently verifiable condition s...

Query DAGs Adnan Darwiche Department of Mathematics American University of Beirut PO Box 11 236 Beirut, Lebanon [email protected] Gregory Provan Department of Diagnostics Rockwell Science Center 1049 Camino Dos Rios Thousand Oaks, Ca 91360 [email protected] Abstract This paper proposes a novel, algorithmindependent approach to optimizing belief network inference. Rather than designing ...

Diacylglycerol (DAG) is a prominent endogenous modulator of synaptic transmission. Recent studies proposed two apparently incompatible pathways, via protein kinase C (PKC) and via Munc13. Here we show how these two pathways converge. First, we confirm that DAG analogs indeed continue to potentiate transmission after PKC inhibition (the Munc13 pathway), but only in neurons that previously experi...

Stack layouts and queue layouts of undirected graphs have been used to model problems in fault tolerant computing and in parallel process scheduling. However, problems in parallel process scheduling are more accurately modeled by stack and queue layouts of directed acyclic graphs (dags). A stack layout of a dag is similar to a stack layout of an undirected graph, with the additional requirement...