The erythroid-cell maturation is characterized by a series of complex morphological and biochemical events which in a relatively short period of time (70h) convert the committed haematopoietic stem cell into the mature anucleate erythrocyte. Despite our progress in the understanding of some aspects of erythropoiesis, the molecular mechanisms which control the progressive disappearance of subcel...

IntroductionCardiologists should be aware of rare diseases that can impact cardiac function. Our case involves a woman with cardiomyopathy and left ventricular (LV) thickening which was mistakenly diagnosed.Case ReportOur patient presented at age 27 in 2018 palpitations dyspnea, eventually being diagnosed multiple pathologies including non-ischemic cardiomyopathy. In 2022, she referred to our A...

Programmed cell death (PCD) is the genetically controlled suicide of cells. The tight regulation of this program is essential to ensure that it is only activated in the required cells at the proper moment. Deregulation of apoptosis, the main form of PCD in animals, is associated with diseases such as cancer, autoimmune diseases, and neurodegenerative disorders (Shi, 2002). In plants, deregulati...

Recently, novel biomolecules separation and detection methods based on ion concentration polarization (ICP) phenomena have been extensively researched due to its high amplification ratio and high-speed accumulation. Despite of these bright advances, the fabrication of conventional ICP devices still have complicated and times-consuming tasks. As an alternative platform, a paper have been recentl...

Gastrointestinal tumors have major place in the statistics of newly developed cancers every year, as the colon cancer is on third place, stomach cancer is on fifth place, and esophageal cancer is also in the top ten of tumors according statistics of cancer incidence. Usually the tumors are detected on advanced III and IV stage, where the perspectives for the patients are not very optimistic (Da...