Several aspects of human physiology and behavior are dominated by 24-h circadian rhythms with key impacts on health and well-being. These include mainly the sleep-wake cycle, vigilance and performance patterns, and some hormone secretions. The rhythms are generated spontaneously by an internal "pacemaker," the suprachiasmatic nuclei within the anterior hypothalamus. This master clock has, for m...

background and objective: depression is commonly reported in patients with obstructive sleep ap- nea/hypopnea syndrome (osas). we aimed to assess the association between osas severity and depressive symptoms in patients with osas. materials and methods : a total of 337 patients with symptoms of osas were visited for psychological testing prior to beginning diagnosis for the syndrome between 201...

Alzheimer's disease and related dementias (ADRD) can cause sleep and behavioral problems that are problematic for ADRD patients and their family caregivers. Light therapy has shown promise as a nonpharmacological treatment, and preliminary studies demonstrate that timed light exposure can consolidate and improve nighttime sleep efficiency, increase daytime wakefulness and reduce evening agitati...

The wheel-running activity rhythm of tree shrews (tupaias; Tupaia belangeri) housed in constant darkness (DD) phase-advanced following a 3-hr light pulse at circadian time (CT) 21. Dark pulses of 3 hr presented to tupaias in bright constant light (LL) did not induce significant phase shifts of the free-running activity rhythm, irrespective of the CT. In dim LL, tupaias showed simultaneous split...

AIMS To investigate factors that may contribute to performance adaptation during permanent night work. METHODS Fifteen healthy subjects participated in an adaptation and baseline night sleep, directly followed by seven simulated eight-hour night shifts (2300 to 0700 hours). At the end of each shift they were taken outside and exposed to natural light for 20 minutes. They then slept from appro...

BACKGROUND Daytime running lights (DRLs) are a safety feature intended to reduce crashes by increasing the contrast between vehicles and the background. AIMS The purpose of this study was to determine whether there is an association between vehicles in the USA being equipped with DRLs and crash rates. METHODS This was a retrospective study using the Minnesota Department of Transportation (M...