To the Editor With interest we read the article by Misumi et al. about a teenage boy with Duchenne muscular dystrophy (DMD) who had developed dilated cardiomyopathy, isolated left-ventricular hypertrabeculation / noncompaction (LVHT), systolic dysfunction, and fatal ventricular tachycardias (1). We have the following comments and concerns. In Fig. 2, the authors attempt to present LVHT on echoc...

Povidone (PVP, polyvinylpyrrolidone) is a mixture of synthetic polymers with molecular weights (between 10,000 and 70,000 Da) comparable to those of the plasma proteins. It is commonly used as an excipient in different pharmaceutical products; in artificial tears and contact lens preservation solutions; as an additive in foodstuffs (E-1202), serving as a support for edulcorants, and in food sup...

Although allergic contact dermatitis (ACD) due to corticosteroids is a well-known and relatively common phenomenon, the systemic administration of corticosteroids only rarely produces skin reactions (systemic contact dermatitis [SCD]). We present the case of a patient with ACD to various corticosteroids, and who subsequently developed SCD to multiple systemic corticosteroids. A 47-year-old man ...

Inhibitors of mTOR are drugs that have recently been introduced in the field of cardiac transplant. Therefore, their side effects have not been completely documented. The most frequent are leucopoenia, dyslipemia, and infections. Their incidence appears to be related with the dosage.1-3 The bilateral edemas are a known complication,4 but its unilateral manifestation has been described only rare...