to evaluate the effectiveness of conjugated estrogen (premarin) and progesterone in twenty-one postmenopausal women who had been menopause one year, we tested during a 6-month period the serum lipoprotein levels in subjects who offered by premarin in dosage of 0.625 milligram for days 1 to 25 and oral medroxy progestrone acetste for days 15 to 25 of a 30-day cycle. twenty-one subjects completed...

UNLABELLED American ginseng (Panax quinquefolius L.) root health benefits include treatment of type 2 diabetes and this study evaluated the hypoglycemic effects of American red ginseng (ARG). ARG roots have increased bioactive phenolic contents, such as cinnamic acid and ferulic acid during the steaming process. The antihyperglycemic effects of methanol fraction extract of ARG, ferulic acid, an...

A number of therapeutic strategies targeting high-density lipoprotein (HDL) cholesterol and reverse cholesterol transport are being developed to halt the progression of atherosclerosis or even induce regression. However, circulating HDL cholesterol levels alone represent an inadequate measure of therapeutic efficacy. Evaluation of the potential effects of HDL-targeted interventions on atheroscl...

OBJECTIVE To find the prevalence of high risk levels of lipoprotein(a) [Lp(a)] and the ratio between low-density lipoprotein (LDL) and high-density lipoprotein (HDL) in patients with type 2 diabetes mellitus (DM) as evidence has been provided that Lp(a) and LDL can act additively in the development of atherogenesis. METHODS This cross sectional study was carried out at the Department of Chemi...

Apolipoprotein CIII (apoCIII) was first identified more than 40 years ago as a component of very-low-density lipoprotein (VLDL)1 and shortly thereafter as an inhibitor of lipoprotein lipase.2 More than a decade later, apoCIII was found to inhibit lipoprotein remnant uptake by the liver.3 Its relevance to human lipid metabolism was made clear by its absence, along with apolipoprotein AI, in 2 si...

BACKGROUND The aim of this study was to determine the role of the chemokine receptor CXCR7 in atherosclerosis and vascular remodeling. CXCR7 is the alternative receptor of CXCL12, which regulates stem cell-mediated vascular repair and limits atherosclerosis via its receptor, CXCR4. METHODS AND RESULTS Wire-induced injury of the carotid artery was performed in mice with a ubiquitous, condition...

conclusions it is speculated that increased insulin resistance and increase in other adipokines such as il-6 may contribute to the decreased serum levels of adiponectin in patients with both cad and t2dm. objectives in this present study, we measured serum adiponectin levels in consecutive cad patients with and without t2dm and investigated whether decreased adiponectin is associated with risk ...

increasing the intensity of physical activity is associated with reduced risk of cardiovascular diseases and this may be the reason why the blood lipoprotein profiles improve. so the aim of this study was to investigate the effect of six weeks of a high intensity interval training (hiit) on lipid profile of sedentary young men. for this purpose, 18 sedentary young men voluntarily participated i...

Introduction: Adipose tissue and inflammatory factors play important role in occurrence of atherosclerosis in overweight women. The present study aimed to investigate the effect of 8 weeks of aerobic exercise training on risk factors involved in atherosclerosis in overweight women. Materials and methods: For this, fourteen overweight women (mean ± standard deviation: body mass index 28....