Background: Hyper-Immunoglobulin M (IgM) syndrome (HIGM) is a rare primary immunodeficiency in which defective B-cell isotype switching results in a phenotype characterized by elevated or normal serum IgM levels and low levels of other Ig classes, leading to an increased susceptibility to infection, neutropenia, autoimmune disorders, and malignancies. In this disease, a mutation occurs in the C...

Dental bleaching occurs due to an oxidation reaction between the bleaching agents and the macromolecules of pigments in the teeth. This reaction is unspecific and the peroxides can also affect the dental matrix causing mineral loss. On the other hand, recent studies have suggested that the thickener agent carbopol can also cause mineral loss. Thus, the objective of this study was to evaluate in...

Epidermolysis bullosa (EB) is a clinically diverse group of conditions characterized by skin fragility and, in certain types, marked dental involvement. The purpose of this study was to determine the prevalence of dental caries in EB and control populations. Healthy individuals and participants from the Southern Clinical Center of the National EB Registry were examined with artificial light and...

A case of trisomy for the short arm of chromosome 9 in a 13-year-old boy is described. Particular emphasis is placed upon a number of abnormal dental findings, which include enamel hypoplasia, hypodontia, and severe dental crowding. The difficulties of providing comprehensive dental treatment in cases such as these is discussed.

objective: the aim of this study was to evaluate the efficacy of enamel bonding agents on pit and fissure sealant retention in a well-isolated situation. materials and methods: thirty-two patients (6-9 years old, all males) with four fully erupted permanent first molars were selected. their occlusal, buccal, and lingual fissures were sealed according to a split-mouth design using concise light ...

path of microleakage between the enamel and adhesive potentially allows microbial ingress that may consequently cause enamel decalcification. the aim of this study was to compare microleakage of brackets bonded either by laser or acid etching techniques.the specimens were 33 extracted premolars that were divided into three groups as the acid etching group (group 1), laser etching with er:yag at...

background: human endeavors to prevent dental caries have led to the use of different modalities and agents, the most commonly used of which is fluoridated dentifrice. an in situ study was carried out to evaluate the efficacy of fluoridated dentifrices in achieving remineralization of initial caries-like lesions using surface microhardness measurements and to study the qualitative changes by sc...

During mammalian tooth development, the oral ectoderm and mesenchyme coordinate their growth and differentiation to give rise to organs with precise shapes, sizes and functions. The initial ingrowth of the dental epithelium and its associated dental mesenchyme gives rise to the tooth bud. Next, the epithelial component folds to give the tooth its shape. Coincident with this process, adjacent ep...