INTRODUCTION Dental pulp has neural fibers that produce neuropeptides like Substance P (SP) and calcitonin gene-related peptide (CGRP). The inflammation of dental pulp can lead to an increase amount of SP and CGRP release, especially in symptomatic irreversible pulpitis. Therefore, it can be assumed that neuropeptides have some role in the progression of inflammation of the dental pulp. The aim...

A routine cavity preparation of a tooth may lead to opening the pulp chamber. The present study evaluates quantitatively, in real time, for the first time to the best of our knowledge, the drilled cavities during dental procedures. An established noninvasive imaging technique, Optical Coherence Tomography (OCT), is used. The main scope is to prevent accidental openings of the dental pulp chambe...

The annual review of selected dental literature this year cites 384 published papers and reports. This year's review contains more editorial comment than reviews of years passed. New data on the biological responses to materials is emphasized in several sections. Observations on new compounds able to prevent plaque formation are presented. Clinically relevant advances in knowledge concerning th...

Mesenchymal stem cells (MSCs) are adult stem cells that have the capacity of rising multiple cell types. A rich source of mesenchymal stem cells is represented by the dental tissues: the periodontal ligament, the dental pulp, the apical papilla, the dental follicle and the deciduous teeth. The aim of this review is to characterize the main dental- derived mesenchymal stem cell population, and t...

The effects of vital root resection upon the remaining pulp were studied in twenty-six periodontally involved human molars. The pulp was extirpated 14 days after the intervention. Granulomatous tissue present in the pulp chamber protruded from the site of the exposure as a polyp in eleven cases. Mild chronic inflammatory changes were present in the coronalmost part of the radicular pulp. The ap...

Dental caries is a chronic infectious disease resulting from the penetration of oral bacteria into the enamel and dentin. Microorganisms subsequently trigger inflammatory responses in the dental pulp. These events can lead to pulp healing if the infection is not too severe following the removal of diseased enamel and dentin tissues and clinical restoration of the tooth. However, chronic inflamm...

INTRODUCTION Microarray is a recently developed simultaneous analysis of expression patterns of thousand of genes. The aim of this research was to evaluate the expression profile of human healthy dental pulp in order to find the presence of genes activated and encoding for proteins involved in the physiological process of human dental pulp. We report data obtained by analyzing expression profil...

introduction: open-apex teeth with irreversible pulpitis require complex and difficult treatment. providing the right environment for apexogenesis and pulp protection is vital for their long term prognosis. the young pulp of open apex tooth, however, is better equipped against irritation and assault. the aim of this study was to evaluate pulp inflammation in open apex canine teeth of cats. mate...

introduction: knowledge of the anatomic location and dimension of the molar pulp chamber may preserve healthy pulp during operative procedure and reduce risk of perforation of chamber during access preparation. a review of literatures regarding the morphology of pulp chamber however revealed very little information; so the aim of this in vivo study was to measure the dimensions of first molar p...

to report the association of pulp calcification with that of cardiovascular disease (cvd) using digital panoramic dental radiographs.digital panoramic radiographs of patients referred from the angiography department were included if the patient was under 55 years old and had non-restored or minimally restored molars and canines. an oral and maxillofacial radiologist evaluated the images for pul...