نتایج جستجو برای: derived growth factor
تعداد نتایج: 1850426 فیلتر نتایج به سال:
Mucormycosis is a life-threatening infection caused by Mucorales fungi. Here we sequence 30 fungal genomes, and perform transcriptomics with three representative Rhizopus and Mucor strains and with human airway epithelial cells during fungal invasion, to reveal key host and fungal determinants contributing to pathogenesis. Analysis of the host transcriptional response to Mucorales reveals plate...
Growth factors regulate a diverse array of cellular functions including proliferation, survival, movement, and the ability to do this often involves interactions with the extracellular matrix (ECM) and particularly heparan sulfate proteoglycans (HSPGs). HSPGs have been shown to sequester growth factors, and to act as growth factor co-receptors or receptors themselves. Recent studies, however, h...
Purpose: We investigated the effect of (bFGF) (basic-Fibroblast Growth Factor) on the differentiation of divided cardiomyocytes from mouse embryonic stem cells (ES) and their pharmacological properties. Materials and Methods: The mouse embryonic stem cells (Royan B1) were cultured as 800 cells per 20µl of a hanging drop. After two days, ES cells in each drop aggregated to form embryoid bodies ...
Non-invasive therapies for the treatment of hepatocellular carcinoma (HCC) would be of great benefit to public health. To this end, we have developed a platelet-derived growth factor-C (PDGF-C) transgenic (Tg) mouse model, which mimics many aspects of human liver carcinogenesis. Specifically, overexpression of PDGF-C results in liver fibrosis, which is preceded by activation and proliferation o...
چ فده قیقحت : هدننک دک یلاوت زا یپک ود یاراد ینایب روتکو تخاس هعلاطم نیا زا فده gdnf نایب یارب یناسنا .تسا نارادناتسپ یلولس هدر رد : قیقحت شور cds نیئتورپ gdnf صخشم یکیتامروفناویب تاعلاطم هلیسو هب یناسنا دیدرگ تفج ود کمک اب . اب هک یرمیارپ رازفا مرن oligo7.4 یحارط دندش رد هناشن دیتپپ ، n و نیئتورپ لانیمرت his-tag رد c نآ لانیمرت شور زا هدافتسا اب .تفرگ رارق t/a cloning روتکو رد هدش دی...
The platelet-derived growth factor (PDGF) family of mitogens exerts vital functions during embryonal development, e.g. in the central nervous system, where PDGF drives the proliferation of oligodendrocyte precursors. PDGF and PDGF receptors are co-expressed in human glioblastoma (GBM). Whether an aberrant activation of the PDGF receptor pathway is a driving force in glioma development has remai...
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