نتایج جستجو برای: dermal toxicity
تعداد نتایج: 133871 فیلتر نتایج به سال:
closure of fascia after transverse rectus abdominis musculocutaneous (tram) flap has usually been performed with direct closure or synthetic material. the dermal autograft was removed from zone iv of flap was an alternative to reinforce fascial closure. the dermal autograft was used in 34 patients after tram harvest for breast, head and neck reconstruction and prolene mesh was used in 42 other ...
OBJECTIVE To evaluate the pharmacokinetics and tissue distribution of liposomal brucine (LB) for dermal application. METHODS Pharmacokinetics and tissue distribution were studied by in vivo animal testing. High performance liquid chromatography (HPLC) was used to detect the concentration of brucine in rats' skin, plasma and various tissues. RESULTS After dermal administration, LB was absorb...
Green tea extract and its principal active ingredient, epigallocatechin gallate (EGCG), are gaining attention and increased usage due to their healthful properties. Despite the increasing demand for these products, few studies have examined their safety. The toxicity of purified green tea extracts containing high concentrations of EGCG have been evaluated in a series of studies in order to defi...
permethrin and cypermethrin are synthetic pyrethroids, belonging to a group of insecticides with low mammalian toxicity and high insecticidal activity. the present study evaluated sub-acute toxicity of dermally administrated permethrin and cypermethrin in mice. behavioral examination included assessments of lethality, weight gain, grooming, analgesymetry, anxiety, grasping, motor activity, and ...
Background & Objectives: Dermal exposure to chemical agents can result in a variety of occupational diseases and disorders, including occupational skin diseases and systemic toxicity . T he present paper focused on transport properties of nanocomposite based on carboxylated nitrile butadiene rubber (XNBR)-nanoclay. Methods: In this study, XNBR gloves nanocomposite were prepared a...
Particulate matter2.5 (PM2.5) is notorious for its strong toxic effects on the cardiovascular, skin, nervous, and reproduction systems. However, the molecular mechanism by which PM2.5 aggravates disease progression is poorly understood, especially in a water-soluble state. In the current study, we investigated the putative physiological effects of aqueous PM2.5 solution on lipoprotein metabolis...
Current pesticide risk assessment does not specifically consider amphibians. Amphibians in the aquatic environment (aquatic life stages or postmetamorphic aquatic amphibians) and terrestrial living juvenile or adult amphibians are assumed to be covered by the risk assessment for aquatic invertebrates and fish, or mammals and birds, respectively. This procedure has been evaluated as being suffic...
BACKGROUND Peripheral neuritis caused by acrylamide is well-known, and many Korean grouting workers are frequently exposed to acrylamide in grouting agents that are injected into cracked concrete. We recently encountered two cases of dermal and neural toxicity in Korean grouting workers with exposure to grouting agents that contained a high concentration of acrylamide. CASE PRESENTATION The f...
The aim of present study was to determine the antipsoriatic activity of newly formulated O/W creams of methanolic extract of Cassia tora L. leaves by using ultraviolet-B-induced psoriasis in rat. The plant Cassia tora L. is traditionally claimed to be useful in the treatment of a number of skin diseases. However, there are no established scientific reports for its antipsoriatic activity. Methan...
The need for test systems for nanoparticle biocompatibility, toxicity, and inflammatory or adaptive immunological responses is paramount. Nanoparticles should be free of microbiological and chemical contaminants, and devoid of toxicity. Nevertheless, in the absence of contamination, these particles may still induce undesired immunological effects in vivo, such as enhanced autoimmunity, hypersen...
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