Dermatofibroma (benign fibrous histiocytoma) represents one of the most common skin tumors. We present the case of a 52 year old female patient with a highly pigmented nodular lesion, localized on the right thigh. Dermoscopy completed the clinical diagnosis, but could not exclude a malignant tumour . Ultrasound examination (Dermascan C sonograms 20 MHz, 2D ultrasound, Doppler ultrasound, contra...

Storiform collagenoma is a rare tumor, which originates from the proliferation of fibroblasts that show increased production of type-I collagen. It is usually found in the face, neck and extremities, but it can also appear in the trunk, scalp and, less frequently, in the oral mucosa and the nail bed. It affects both sexes, with a slight female predominance. It may be solitary or multiple, the l...

Received July 18, 2011, Revised August 4, 2011, Accepted for publication August 4, 2011 Corresponding author: Kee Suck Suh, M.D., Department of Dermatology, Kosin University College of Medicine, 262 Gamcheon-ro, Seo-gu, Busan 602-702, Korea. Tel: 82-51-990-6145, Fax: 82-51-990-3041, E-mail: [email protected] This is an Open Access article distributed under the terms of the Creative Commons ...

BACKGROUND The effects of the Notch signaling pathway in fibroproliferative skin diseases have not been fully elucidated. OBJECTIVE The aim of this study was to investigate the expression of activated Notch signaling molecules in various skin fibroproliferative diseases. METHODS Immunohistochemical analysis of Notch intracellular domain (NICD) expression in keloid, hypertrophic scar, morphe...

A series of nine cases of fibroma of tendon sheath is described including details of the ultrastructural features of two cases. The series was composed of lesions from six males and three females with a mean age of 38 yr. The most common site of involvement was the hand (including fingers) and the mean greater diameter was 19 mm. Typically the tumours were lobulated and microscopically there wa...

CASE REPORTS Case 1-A boy aged six months was seen in 1969 because of a swelling on the back of the distal part of the right middle finger. He was the fourth child of healthy parents. The tumour had appeared in the third month of life ; it was about 5 millimetres in diameter, firm, not tender, and fixed to the skin but not to the underlying tissues. Biopsy showed a dermatofibroma with no sign o...

Skin cancer is one of the most common cancers, and its early detection can have a huge impact on outcomes. Deep learning, especially convolutional neural networks, perform well in processing massive amounts data, image data classifying skin cancer. In this paper, networks are mainly used to diagnose classify 7 types lesions, including melanoma, basal cell carcinoma, melanocytic nevus, actinic k...

Several variants of atypical fibroxanthoma (AFX) are split based on cytomorphology, for example, clear cell, granular cell, and spindle cell nonpleomorphic types. Nine cases of an unusual variant of AFX with keloidal tumoral sclerosis were presented by Kim and McNiff, following in from an anecdotal report and series of ‘‘keloidal’’ AFX. In several cases, ‘‘the keloidal collagen also formed ring...