introduction: to describe the underlay tympanoplasty technique using an acellular dermal graft(alloderm) for tympanic membrane (tm) reconstruction in a guinea pig model and to demonstrate the feasibility of the technique using alloderm tissue harvested from the prepuce as a source of tissue for future grafting in human tm reconstruction.   materials and methods: the prepuce was divided during c...

BACKGROUND The survival rate of grafted fat is difficult to predict, and repeated procedures are frequently required. In this study, the effects of the freezing period of harvested adipose tissue and the addition of human adipose tissue-derived stem cells (ASCs) on the process of fat absorption were studied. METHODS Adipose tissue was obtained from patients who underwent a lipoaspirated fat g...

1. Bucky LP, Kanchwala SK. The role of autologous fat and alternative fillers in the aging face. Plast Reconstr Surg 2007;120:89S-97S. 2. Valdatta L, Thione A, Buoro M, et al. A case of lifethreatening sepsis after breast augmentation by fat injection. Aesthetic Plast Surg 2001;25:347-9. 3. Gutowski KA; ASPS Fat Graft Task Force. Current applications and safety of autologous fat grafts: a repor...

We have observed and re-evaluated the histology of the skin of the horse, using samples from four Thoroughbreds. The skin was composed of the usual three components: epidermis, dermis and subcutis. In particular, the dermis was found to have three fibrous components: a papillary layer, a reticular layer and a cordovan-leather tissue layer. The cordovan-leather tissue layer was subdivided into a...

A white 30-year-old woman presented with a 4-year history of a nodular lesion of the face that appeared to be growing and changing colour. Surgical excision without histolopathoogical examination 3 years previously for the same lesion had resulted in a relapse 3 months later. Physical examination showed a 1.3 cm erythematous, violaceous, multi-lobed tumour, with 2 pigmented satellite nodules on...

background: considering the common origin of skin and peripheral nervous system, a tube of dermal layer of skin hypothetically can be an ideal conduit for nerve reconstruction. an experimental study performed to evaluate the nerve regeneration of efficacy into a dermal tube. methods: sixty male wistar rats were used. a 10 mm gap was produced in right sciatic nerves. in group a the autogenous ne...

BACKGROUND The increased resorption and the difficulty of the fat graft take following autologous fat transplantation procedure are associated with reduced fat tissue revascularization and increased apoptosis of adipose cells. We suppose that the lipofilling procedure induces an inflammatory environment within the fat graft mass, whose evolution influences the efficacy of autologous fat graft s...

OBJECTIVE To compare various graft materials in the rabbit model, including autologous cartilage, dermal tissue, fat, and AlloDerm (a cadaver-derived material). METHODS Twenty-five New Zealand white rabbits were used. Equally sized autogenous (fat, fascia, cartilage, and dermal) grafts and AlloDerm were implanted into subcutaneous dorsal pockets on the rabbits. Animals were killed 1, 2, 3, an...

Two cases of naevus lipomatosus superficialis (Hoffmann and Zurhelle) are described by the authors. The main clinical characteristics and histological peculiarities are reviewed. Both cases were disseminated and had typical localisation (pelvic area). The histological examination showed ectopic adipocytes in the dermis. The authors mare a reference to the different hypotheses on the pathogenesi...