tau.amegroups.com © Translational Andrology and Urology. All rights reserved. World Health Organization (WHO) defines infertility as the inability of a sexually active, non-contraceptive couple to achieve pregnancy in 1 year (1). Overall, the worldwide incidence is about 15 % and a male factor is responsible in 20–50% of cases (2). Medical history, physical examination and semen analysis remain...

Abstract Study question In men with Raised Sperm DNA Fragmentation Index (DFI), Would advance sperm preparation techniques at Intra-Cytoplasmic Injection (ICSI) alter embryo euploidy status? Summary answer raised DFI, use of selection are safe and do not appear to ploidy status the embryos What is known already MACS (Magnetic Activated Cell Sorting), Microfluidic Sorting (MF), surgically retrie...

OBJECTIVE To examine sperm DNA fragmentation in semen used for assisted reproduction procedures to establish this factor's prognostic role in fertilization rate, embryo development, pregnancy rate, and outcome. DESIGN Prospective study. SETTING Department of Medicine and Biology of Reproduction of the Edouard Herriot Hospital in Lyon, France. PATIENT(S) 322 couples, divided into 88 cycles...

It has been postulated that changes in lifestyle follow five 'stages of change', which reflect a 'decisional balance' between the advantages and disadvantages of making such a change. We have assessed this model among Pacific Islands people in New Zealand. We questioned 105 Pacific Islands volunteers to identify their decisional balance for their reduction in dietary fat intake (DFI), weight co...

OBJECTIVE To examine the relationship among sperm apoptosis, sperm chromatin status, and DNA ploidy in different sperm fractions. DESIGN Prospective study. SETTING Reproductive research center in a tertiary care hospital. INTERVENTION(S) Sperm prepared by density gradient were evaluated for sperm count, motility, apoptosis, and sperm chromatin assessment. MAIN OUTCOME MEASURE(S) Sperm c...

INTRODUCTION The long-term prognosis of induction chemotherapy followed by surgery for N2 non-small lung cell cancer (NSCLC) remains controversial. PATIENTS AND METHODS We retrospectively reviewed the data and assessed the prognosis of 31 N2-NSCLC patients who underwent induction chemotherapy followed by surgery at our institution between January 1999 and December 2013. Potential prognostic f...

It has been known for some time that high-temperature superconductors (HTS) are critical for the construction of NMR magnets generating 1 GHz and above. Such systems generally require an HTS insert to be placed in the inner high-field region of a low temperature superconducting (LTS) magnet. Among the problems in the presently available HTS technology are splice resistance and index dissipation...

This paper examines negotiation as a means of conflict resolution among participants involved in the design, manufacture and assembly process of designing connections in buildings. A distributed problem-solvlng (DPS) architecture which models participants as semi-autonomous computer "agents" which reason from their perspectives during design evaluation is presented. The system, called the Desig...

The two classical immunophilin families, found essentially in all living cells, are: cyclophilin (CYN) and FK506-binding protein (FKBP). We previously reported a novel class of immunophilins that are natural chimera of these two, which we named dual-family immunophilin (DFI). The DFIs were found in either of two conformations: CYN-linker-FKBP (CFBP) or FKBP-3TPR-CYN (FCBP). While the 3TPR domai...