objectives this study aimed to investigate the relation between depression and quality of life in patients with diabetes. patients and methods this is a cross sectional survey. subjects were selected from 330 eligible people referred to the only diabetes clinic in gorgan city during 6 months, using systematic random sampling. beak depression questionnaire and the brief questioner with 26 questi...

conclusions our findings showed that the genotype tt rs53576 oxtr, as well as t allele had significant differences in our population and play a protective role. therefore, it is suggested to place more interest on these oxtr in large populations and different ethnic groups. results the logistic regression analysis suggested no significant associations of oxtr single nucleotide polymorphism (snp...

conclusions: the prevalence of obesity in patients with type 2 diabetes mellitus in yemen is high with respect to the yemeni population, especially in females. objectives: we conducted this study to assess the prevalence of obesity in yemeni patients with type 2 diabetes mellitus. patients and methods: body mass index (bmi) of patients with type 2 diabetes mellitus who were 25-years-old or olde...

context since 2006 a relevant number of therapeutical algorithms for the management of type 2 diabetes have been proposed, generating a lively debate in the scientific community, particularly on the ideal timing for introduction of insulin therapy and on which drug should be preferred as add-on therapy in patients failing to metformin. at the moment, there is no real consensus. the aim of the p...

results apoptosis induced by pa in ins-1 cells was significantly resolved after liraglutide treatment. simultaneously, autophagy was enhanced with the treatment of pa and liraglutide. conclusions: liraglutide appears to protect ins-1 cells from apoptosis ffa-induced by promoting autophagy. conclusions these findings provide a novel role for glp-1 analogue in preventing or treating with t2d. obj...

background: low serum 25-hydroxy vitamin d (25(oh)d) has been shown to correlate with an increased risk of type 2 diabetes mellitus (t2dm). the objective of this study was to investigate the association between serum 25(oh)d and glycemic and inflammatory markers in non-obese patients with t2dm. methods: eighty-four non-obese patients with t2dm were recruited in this cross-sectional study. demog...

background impaired fasting glucose (ifg), and impaired glucose tolerance (igt) are two prediabetes conditions which have some correlation with macrovascular disorders. the risk of microvascular complications in these groups is not clear. objectives the prevalence of albuminuria in subjects with ifg and igt was evaluated in the present study. patients and methods in this study three groups of s...

objective: to evaluate the relationship between serum level of testosterone and sex hormone-binding globulin in men with type 2 diabetes. materials and methods: in this case-control study, forty men aged 40-70 with type 2 diabetes mellitus were randomly selected and compared with 40 non-diabetic men. the two groups were matched for their age and bmi. after complete observation and examination, ...

objective: to evaluate the relation between major depressions and glucose control index in type 2 diabetes mellitus. materials and methods: one- hundred thirty four patients with type 2 diabetes were enrolled in this study. hamilton rating scale for depression (ham-d) and hba1c were measured in patients. linear mixed-model analysis was applied to determine the relation between hba1c levels and ...

objective: we aimed to evaluate association between thyroid dysfunction, and lipid profile and glycated hemoglobin in type 2 diabetic patients. materials and methods: this cross-sectional study was carried out in type 2 diabetic patients who referred to yazd diabetes research center. a total of 1200 type 2 diabetic patients who had thyroid dysfunction according to clinical examinations and labo...