objectives: diabetes mellitus is associated with biochemical, physiological and pathological alterations in the liver. the aim of this study was to investigate the effects of hydroalcoholic extract of prangos ferulacea (l.) lindle (p.f) on changes in rats´ liver structure and serum activities of alanin and aspartate aminotransferases after alloxan injection. materials and methods: in this study...

diabetes mellitus is associated with complications in several different systems of the body, and the incidence of diabetes is rapidly increasing worldwide. the objective of the present study was to evaluate the effect of aqueous extract of cydonia oblonga mill. fruit on lipid profile and some biochemical parameters in streptozotocin-induced diabetic rats. the extract showed anti hyper lipidemic...

background: oral vanadyl sulfate (vanadium) induces normoglycemia, proliferates beta cells and prevents pancreatic islet atrophy in streptozotocin-induced diabetic rats. soteriological method is used to quantitate the proliferative effects of vanadium on beta-cell numbers and islet volumes of normal and diabetic rats. methods: adult male sprague-dawley rats were made diabetic with intravenous s...

background: pomegranate seed oil and its main constituent, punicic acid, have been shown to decrease plasma glucose and have antioxidant activity. the objective of the present study was to examine the effects of pomegranate seed oil on rats with type 2 diabetes mellitus. method: six groups (n=8 each) of male sprague-dawley rats, comprising a control, a diabetic (induced by streptozocin and nico...

Objective(s): Diabetes mellitus is a public health problem and one of the five leading causes of death globally. In the present study, the effect of Metformin with natural honey was investigated on glycemia in the Streptozotocin-induced diabetic rats. Materials and Methods: Thirty Wistar male rats were randomly divided into six groups including C: non ‌diabetic rats received distilled water, C...

The present study aimed to investigate the role of adenylyl cyclase activator in preventing diabetic nephropathy via antioxidant activity in rats. Biochemical parameters were performed to confirm Streptozotocin induced nephropathy in rats. Male Wistar rats were used in the present study to reduce the effect of estrogen. Rats were subjected to high fat diet (HFD) for two weeks followed by low do...

Diabetes is the most important growing health risk throughout World. In this study, antidiabetic effects of ginger extract were investigated through measurements metabolic hormones irisin and hepcidin, liver function enzymes hematological analysis. Forty female, healthy Wistar albino rats divided into 5 groups: Control, Sham, Diabetic, Ginger (200 mg/kgbw) Ginger+Diabetes group mg/kgbw). While ...

Oxidative stress and inflammation are connected to the development of metabolic disorders, such as diabetes. Diabetic-related oxidative is caused by overproduction oxidative-free radicals, which have been implicated in mechanism damage tissues. Our study aimed investigate effects ubiquinone treatment on serum indicators (malondialdehyde (MDA)), (interleukin 6 (IL-6)), vascular homeostasis (nitr...