Eukaryotic and archaeal DRG factors are highly conserved proteins with characteristic GTPase motifs. This suggests their implication in a central biological process, which has so far escaped detection. We show here that the two Saccharomyces cerevisiae DRGs form distinct complexes, RBG1 and RBG2, and that the former co-fractionate with translating ribosomes. A genetic screen for triple syntheti...

The aim of this study was to analyse the inpatient statistics collection relating to stroke patients admitted to a major teaching hospital, with particular reference to length of stay, and to assess the adequacy of the diagnosis related group (DRG) as a predictor of length of stay. The study subjects were selected by DRG to identify all stroke inpatients admitted and discharged between 1 July 1...

OBJECTIVES The Disease-Related Groups (DRGs) system postulates that inpatient stays with similar levels of clinical complexity are expected to consume similar amounts of resources. This, applied to surgery of congenital heart disease, suggests that the higher the complexity of procedures as estimated by the Aristotle complexity score, the higher hospital reimbursement should be. This study anal...

(MedPAC) involves comparing costs with payment rates — an approach that does not identify services whose utilization is increasing because prices are set too high. Japan has taken a different approach in responding to high rates of utilization, by monitoring specific services whose use grows substantially, rather than lumping all physician procedures together. In the United States, line-item re...

Voltage-dependent Ca(2+) channels are structurally and functionally diverse. As Ca(2+) currents recorded from embryonic chick dorsal root ganglion (DRG) neurons differ significantly from their mammalian counterparts, information on the primary sequence of the chick channels will help define the structural underpinnings of Ca(2+) channel function. Here, we report the cloning and functional expre...

The unpredictable French health care reform of 1995-96 introduced casemix tools to fund French hospitals at a regional level. After two years (1997-98), health care authorities and hospitals are facing great inequities and inefficiencies (1 to 3) in 22 French regions. Only one region (Ile de France, Paris) is above the national casemix index mean, the Index Synthétique d' Activité, and very few...

Objectives The aims of this study were to compare the performance of machine learning methods for the prediction of the medical costs associated with spinal fusion in terms of profit or loss in Taiwan Diagnosis-Related Groups (Tw-DRGs) and to apply these methods to explore the important factors associated with the medical costs of spinal fusion. Methods A data set was obtained from a regional...

Objectives The aim of this article is to study patient satisfaction with complementary and alternative medicine (CAM) in an in-hospital setting before and after the introduction of diagnosis-related groups (DRGs). Methods Patients were interviewed regarding a general evaluation of their hospital stay, the psychological talking therapy, the nutrition therapy, and the overall success of the tre...

BACKGROUND Switzerland introduces a DRG (Diagnosis Related Groups) based system for hospital financing in 2012 in order to increase efficiency and transparency of Swiss health care. DRG-based hospital reimbursement is not simultaneously realized in all Swiss cantons and several cantons already implemented DRG-based financing irrespective of the national agenda, a setting that provides an opport...

On December 21st 2007, the Swiss Federal Parliament passed the new financing of hospital care through a DRGbased performance payment system (SwissDRG). The new financing method is due to come into force on January 1st 2012 and hospitals are now facing the challenge of adapting their cost accounting systems to support both the tariff negotiation process with health insurers and the internal stra...