نتایج جستجو برای: digital microfluidic biochip

تعداد نتایج: 325478  

2012
Min-Yu Chiang Shih-Kang Fan

We demonstrate an integrated platform combining (1) digital microfluidic and (2) photo-patterning techniques to manipulate and fabricate cell-laden hydrogels for the tissue engineering application. Different hydrogels cured from individuallydriven polymer droplets provide three-dimensional (3D) microenvironments for in vitro cell culture. With the ability to actively drive the polymer droplets,...

2016
MALTE KÜHNEMUND Sten Linnarsson

Kühnemund, M. 2016. Single Molecule Detection. Microfluidic Automation and Digital Quantification. Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine 1189. 57 pp. Uppsala: Acta Universitatis Upsaliensis. ISBN 978-91-554-9498-8. Much of recent progress in medical research and diagnostics has been enabled through the advances in molecular analysis technologies, ...

Journal: :Optik & Photonik 2008

2014
Y. Cao M. R. Zamani

Recently, tape&film based microfabrication method has been studied for rapid prototyping of microfluidic devices due to its low cost and ease of fabrication [1]. But most of the reported film-based microfluidic devices are simple single-layer patterned 2D designs, whose potential applications are limited. In this paper, we present the design, fabrication and testing results of a 3D structured m...

Journal: :Lab on a chip 2010
Douglas Taylor David Dyer Valerie Lew Michelle Khine

This paper presents a rapid, ultra-low-cost approach to fabricate microfluidic devices using a polyolefin shrink film and a digital craft cutter. The shrinking process (with a 95% reduction in area) results in relatively uniform and consistent microfluidic channels with smooth surfaces, vertical sidewalls, and high aspect ratio channels with lateral resolutions well beyond the tool used to cut ...

Journal: :Lab on a chip 2010
Po Ki Yuen Vasiliy N Goral

Low-cost and straight forward rapid prototyping of flexible microfluidic devices using a desktop digital craft cutter is presented. This rapid prototyping method can consistently achieve microchannels as thin as 200 microm in width and can be used to fabricate three-dimensional (3D) microfluidic devices using only double-sided pressure sensitive adhesive (PSA) tape and laser printer transparenc...

Journal: :Clinical chemistry 2011
Ramakrishna S Sista Allen E Eckhardt Tong Wang Carrie Graham Jeremy L Rouse Scott M Norton Vijay Srinivasan Michael G Pollack Adviye A Tolun Deeksha Bali David S Millington Vamsee K Pamula

BACKGROUND Newborn screening for lysosomal storage diseases (LSDs) has been gaining considerable interest owing to the availability of enzyme replacement therapies. We present a digital microfluidic platform to perform rapid, multiplexed enzymatic analysis of acid α-glucosidase (GAA) and acid α-galactosidase to screen for Pompe and Fabry disorders. The results were compared with those obtained ...

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