A series of 1-(2,4-dinitrophenyl)-3-(3-nitrophenyl)-5-(4-substituted phenyl)-2-pyrazolin-4-ones (4a-e) have been synthesized by the oxidation of 1-(2,4-dinitrophenyl)-3-(3-nitrophenyl)-5-(4-substituted phenyl)-4-bromo-2-pyrazolines (3a-e) with dimethylsulfoxide. The structure has been established on the basis of spectral data (IR,1H NMR). The synthesized compounds have been screened in vitro fo...

Following our previous paper, we exammed the effects on the heme synthesis in quail yolk sac cells of polar compounds, other than dimethyl sulfoxide. that induce erythroid cell differentiation in cultured Friend leukemia cells. Dissociated yolk sac cells from quail embryos at the definitive primitive streak stage were cultured in a gyratory shaker in a medium containing dimethyl sulfoxide or ot...

The asymmetric unit of the title compound, tetra-aqua-tetrakis-{μ(3)-6,6'-di-oxido-2,2'-[1,2-phenyl-enebis(nitrilo-methyl-idyne)]diphenolato}octa-zinc(II) dimethyl sulfoxide tetra-solvate dihydrate, [Zn(8)(C(20)H(12)N(2)O(4))(4)(H(2)O)(4)]·4C(2)H(6)OS·2H(2)O, contains one quarter of a Zn(II) octa-nuclear complex with symmetry, one dimethyl sulfoxide mol-ecule and one half of a water mol-ecule w...

Following our previous paper, we exammed the effects on the heme synthesis in quail yolk sac cells of polar compounds, other than dimethyl sulfoxide. that induce erythroid cell differentiation in cultured Friend leukemia cells. Dissociated yolk sac cells from quail embryos at the definitive primitive streak stage were cultured in a gyratory shaker in a medium containing dimethyl sulfoxide or ot...

Cell fusion with two genetically marked Friend (murine erythroleukemia) cells has made it possible to characterize the very early events leading to erythroid differentiation, particularly the nature of reactions initiated by inducers such as dimethyl sulfoxide. We have found that brief exposure of Friend cells to dimethyl sulfoxide (as well as butyric acid or hexamethylene-bisacetamide) induces...

We have studied the effects of sodium butyrate, retinoic acid, and dimethyl sulfoxide on two human ovarian carcinoma cell lines PE04 and PE01. PE04 cells, after treatment with sodium butyrate at cytostatic doses (2-3 mM for 4 days), exhibited phenotypic changes including induction of alkaline phosphatase and determinants recognized by the monoclonal antibodies 123C3 and 123A8. These effects are...

The title compound, C(20)H(20)N(6), was isolated from dimethyl sulfoxide solution using 2-(1H-imidazol-2-yl)pyridine and 1,4-dichloro-butane in the presence of NaOH.