Adrenalectomized dogs maintained on desoxycorticosterone acetate developed a fatal circulatory collapse when given normal dog plasma. They showed general restlessness, a rapid fall in blood pressure and cardiac index, a decline in central venous pressure and general prostration. Most dogs developed a bloody diarrhea and a minority showed edematous swelling of the face with itching. Animals with...

Materials and Methods: Patients over 17 years of age who presented with vertigo as a chief complaint were included in the study. 2 mg diazepam, 50 mg diphenhydramine, or 50 mg dimenhydrinate were given IV over 2 min. Patients evaluated their vertigo perception with Likert numeric (1-10) scale during walking, standing, sitting, and supine positions. Patients also evaluated additional symptoms an...

The aim of the present study was to establish antihistamines drug prescribing pattern in order to improve the rational prescribing of antihistamines by physicians at Panjab University Health Centre. The study was performed in between the months of November 2005 to April 2006. Five hundred out patients were monitored and data was collected on WHO-based prescription-auditing performa. Demographic...

Effects of leukotriene (LT) C4 and LTD4 on coronary artery spasm in atherosclerotic miniature pigs were examined angiographically. Endothelial balloon denudation of the left circumflex coronary artery was performed in 15 Göttingen miniature pigs; 11 were fed a 2% cholesterol diet and four were fed a regular diet for 3 months. Three months after this denudation, the area of the coronary artery w...

The aim of this double-blinded, vehicle-controlled study was to test the antipruritic efficacy of topical strontium to relieve a nonhistaminergic form of itch that would be clinically relevant for chronic pruritic diseases. Itch induced with cowhage is mediated by PAR2 receptors which are considered to play a major role in itch of atopic dermatitis and possibly other acute and chronic pruritic ...