Background While DE imaging is considered a gold standard in the evaluation of myocardial scar/viability in patients with old MI or cardiomyopathy, a few recent publications demonstrate a higher diagnostic sensitivity of T2weighted techniques in patients with Non-STEMI and myocarditis where changes in T2-weighting are due to inflammation in the myocardium leading to edema (Abdel-Aty H, JACC 53:...

The purpose of this study was to identify characteristics of everyday listening situations that influence user preferences for omnidirectional versus directional hearing aid microphones. Eleven experienced hearing aid users were fitted with digital hearing aids featuring switchable omnidirectional (OMNI) and adaptive-directional (DIR) modes (programs). For 6 weeks, their task was to identify an...

BACKGROUND Over time, exposure to cerebrovascular risk factors and carotid artery disease may cause multiple asymptomatic brain cortical and subcortical microinfarcts, which are commonly found at brain autopsy. So far, lack of convenient neuroimaging tools limited the investigation of grey matter ischemic damage in vivo. We applied the Double Inversion Recovery (DIR) sequence to explore the imp...

Result rankings from context-aware information retrieval are inherently dynamic, as the same query can lead to significantly different outcomes in different contexts. For example, the search term Digital Camera will lead to different – albeit potentially overlapping – results in the contexts Customer Reviews and Shops, respectively. The comparison of such result rankings can provide useful insi...

The Drosophila insulin receptor (DIR) contains a 368-amino-acid COOH-terminal extension that contains several tyrosine phosphorylation sites in YXXM motifs. This extension is absent from the human insulin receptor but resembles a region in insulin receptor substrate (IRS) proteins which binds to the phosphatidylinositol (PI) 3-kinase and mediates mitogenesis. The function of a chimeric DIR cont...

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PURPOSE Focal therapy has been proposed as an alternative method to whole-gland treatment for prostate cancer when aiming to reduce treatment side effects. The authors recently validated a radiobiological model which takes into account tumor location and tumor characteristics including tumor cell density, Gleason score, and hypoxia in order to plan optimal dose distributions for focal therapy. ...

PURPOSE Deformable image registration (DIR) is necessary for accurate dose accumulation between multiple radiotherapy image sets. DIR algorithms can suffer from inverse and transitivity inconsistencies. When using deformation vector fields (DVFs) that exhibit inverse-inconsistency and are nontransitive, dose accumulation on a given image set via different image pathways will lead to different a...

introduction: the dominant approach in the etiology and treatment of autism spectrum disorder (asd) is a behavioral approach. proponents of the behavioral model believe that children with autism in access to capabilities in achieving love, empathy, language and creative thinking, have significant fundamental defects.  instead model-based development of individual differences relationship offers...

Objective Ischemia/reperfusion (I/R) injury is an important cause of myocardial damage by means of oxidative, inflammatory, and apoptotic mechanisms. The aim of the present study was to examine the potential cardio protective effects of levosimendan in a diabetic rat model of myocardial I/R injury. Methods A total of 18 streptozotocin-induced diabetic Wistar Albino rats (55 mg/kg) were randomly...