The Securities and Exchange Commission (SEC) has mandated new disclosure requirements in Form 8-K, which became effective on August 23, 2004. The SEC expanded the list of items that have to be reported and accelerated the timeliness of these reports. This study examines the market reactions to 8-Ks filed under the new SEC regime and investigates whether periodic reports (10-K/Qs) became less in...

On December 6, 2007, the Society for Medicines Research held a one-day meeting entitled Recent Disclosures of Clinical Drug Candidates. The meeting brought together speakers from around the world representing both the pharmaceutical industry and academia. The meeting provided an overview of some of the latest approaches being taken in a range of therapeutic areas such as oncology, immunology, c...

VRE (all allo), one coagulase-negative staphylococcus (allo), one Corynebacterium jeikeium (allo), one MRSA (auto), and one viridans streptococcus (auto). Conclusion. Prospective screening of all patients admitted for auto and allo HCT at a large tertiary care cancer center with a geographically diverse referral pattern showed low admission prevalence of FQ-R and negligible ESBL and CR carriage...

We examine whether stress-test disclosures distort banks’risk-taking decisions. We study a model in which a regulator may choose to rescue banks in the event of concurrent bank failures. Our analysis reveals a novel coordination role of stress-test disclosures. By disclosing stress tests, a regulator informs all banks of the failure likelihood of other banks, which facilitates bank’s coordinati...

Video Link The video component of this article can be found at http://www.jove.com/video/205/ Disclosures The authors have nothing to disclose.

Purpose: In 2015, the Centers for Medicare and Medicaid Services ruled that health organizations comply with additional requirements for electronic health records (EHRs), known as "Meaningful Use," and develop the capacity to collect gender identity data. Research has established effectiveness of a two-step gender identity question to collect these data. This study examines transgender patient ...

BACKGROUND Clinical practice guidelines are widely distributed by medical associations and relied upon by physicians for the best available clinical evidence. International findings report that financial conflicts of interest (FCOI) with drug companies may influence drug recommendations and are common among guideline authors. There is no comparable study on exclusively Canadian guidelines; ther...

BACKGROUND Conflict of interest (COI) is an important potential source of bias in the development of clinical practice guidelines (CPGs). OBJECTIVES To examine rates of disclosure of COI, including financial interests in companies that manufacture drugs that are recommended in CPGs on glycemic control in type 2 diabetes mellitus, and to explore the relationship between recommendations for spe...

Video Link The video component of this article can be found at http://www.jove.com/video/272/ Disclosures The authors have nothing to disclose.

S45 Fallenberg E.M.: Advisory Board; Bayer. Research/Grant Support; GE Healthcare, Siemens Healthcare, Bayer. Speaker; GE Healthcare, Siemens Healthcare, Bayer. Froehlich J.M.: Consultant; Guerbet. Frydrychowicz A.: Research/Grant Support; Scientific stipend Bracco Diagnostics. Other; The University of Wisconsin Madison receives research support from GE Healthcare. Fürst S.: Employee; B.W. Jako...