We present a numerical case study for modeling and simulation of upstream downstream processes monoclonal antibody (mAb) production. apply systematic intuitive methodology an existing process process. The resulting models are based on differential mass balances kinetic expressions the reactions adsorption. Mass fedbatch reactor yield model consisting five ordinary equations (ODEs). is conducted...

heat transfer phenomena in batch fluidized bed dryer have been studied and analyzed using three phase model including solid phase, interstitial gas phase and bubble phase based on rizzi model. new correlations of heat transfer coefficient to surrounding and convection heat transfer coefficient between solid and interstitial gas are being proposed. in addition, some modifications have been done ...

For undergraduate mathematical modeling courses, a successful semester project can reinforce key learning objectives while enabling creativity and developing critical thinking skills. However, course directors often struggle in novel ideas balancing the tradeoff between grading burden complexity. At U.S Military Academy, we take an open-ended discovery-learning approach to freshman level math p...