to determine the addition of value of neoadjuvant, concurrent and adjuvant chemotherapy to radiation in the treatment of nasopharyngeal carcinoma with regard to the overall survival (os) and disease free survival (dfs) within a six year period in tehran cancer institute. files of all patients with nasopharyngeal carcinoma treated by radiotherapy with or without concurrent chemotherapy in a cura...

there is a continuing need to identify new agents that are active in ovarian cancer. etoposide is a derivative of the plant alkaloid epipodophyllotoxin. the availability of etoposide in oral preparation allows prolonged administration by the oral route. in this study, activity and toxicity of etoposide in women with recurrent ovarian cancer are described from a case series of women with recurre...

OBJECTIVE To investigate the clinical outcomes of patients who underwent radical cystectomy for bladder cancer at a single institution and compare those who had pT0 specimens with those who had residual cancer. METHODS From January 1990 to December 2006, 186 patients underwent radical cystectomy with or without neoadjuvant chemotherapy for cT2 or higher stage urothelial carcinoma in the bladd...

OBJECTIVE To report the outcome of surgical salvage performed for early-stage squamous cell carcinoma of the glottic larynx that recurred or progressed after definitive radiotherapy. DESIGN Retrospective outcome analysis. SETTING Tertiary referral center specializing in head and neck cancer. PATIENTS Forty-three patients who underwent salvage surgery after definitive radiation therapy for...

BACKGROUND The oral cavity is the most common site for head and neck squamous cell carcinoma. Treatment of advanced stage oral cavity squamous cell carcinoma (OCSCC) has classically involved surgical resection with postoperative adjuvant radiotherapy (S-RT).Despite this aggressive dual modality therapy, the disease outcomes have remained poor. The treatment options expanded in 2004 when two int...

OBJECTIVE To compare long term survival after minimally invasive lobectomy and thoracotomy lobectomy. DESIGN Propensity matched analysis. SETTING Surveillance, Epidemiology and End Results (SEER)-Medicare database. PARTICIPANTS All patients with lung cancer from 2007 to 2009 undergoing lobectomy. MAIN OUTCOME MEASURE Influence of less invasive thoracoscopic surgery on overall survival, ...

Background: The activity and toxicity of etoposide in women with recurrent ovarian cancer was evaluated in a case series of women with recurrent ovarian cancer who had measurable disease, Methods: All patients had plior platinum-based chemotherapy and developed progressive disease, Etoposide was given as 50mg/day for 21 days every 4 weeks until progression of disease or prohibitive toxicit...

BACKGROUND Inflammatory responses play decisive roles in tumor development, immune surveillance, and responses to therapy. High neutrophil-to-lymphocyte ratio (NLR), as an inflammation index, has been reported to be a predictor for poor prognosis of various cancers. The purpose of this meta-analysis was to evaluate the prognostic value of NLR in patients with rectal cancer. METHODS A comprehe...