نتایج جستجو برای: disproportionate growth

تعداد نتایج: 823441  

2009

Mutations or deletions of the SHOX gene, located in the PAR1 region, are involved in idiopathic growth retardation. The SHOX gene escapes X inactivation in females. The growth failure of Turner Syndrome (X0) females is most likely the result of the presence of only one SHOX gene copy in each diploid cell (haploinsufficiency). The tall stature observed in Klinefelter (XXY) syndrome and in Triple...

Journal: :Journal of medical genetics 1985
G N Wilson S E Sauder M Bush I Z Beitins

A male child with features of the Russell-Silver syndrome, including pre- and postnatal growth delay, triangular facies, bilateral fifth finger clinodactyly, and disproportionate lower extremities, was found to have a ring chromosome 15 in all peripheral leucocytes examined. Review of the reported cases of ring chromosome 15 defines a malformation syndrome with a characteristic facies related t...

Journal: :Bulletin of the Chemical Society of Japan 1983

2005
Frank Ellis

Nevertheless, the persistence, and even deepening, in Sub-Saharan Africa of a type of small farming that is getting smaller all the time and that demonstrates an even greater orientation toward low-level subsistence than was the case 20 or 30 years ago should be of great concern to all those working on poverty reduction objectives in the continent. The dynamics of small farming in Africa are po...

Journal: :The Journal of clinical investigation 2012
Michael E Doche Elena G Bochukova Hsiao-Wen Su Laura R Pearce Julia M Keogh Elana Henning Joel M Cline Sadia Saeed Anne Dale Tim Cheetham Inês Barroso Lawrence S Argetsinger Stephen O'Rahilly Liangyou Rui Christin Carter-Su I Sadaf Farooqi

Src homology 2 B adapter protein 1 (SH2B1) modulates signaling by a variety of ligands that bind to receptor tyrosine kinases or JAK-associated cytokine receptors, including leptin, insulin, growth hormone (GH), and nerve growth factor (NGF). Targeted deletion of Sh2b1 in mice results in increased food intake, obesity, and insulin resistance, with an intermediate phenotype seen in heterozygous ...

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