Cutaneous biopsies (n = 94) obtained from 88 patients with American tegumentary leishmaniasis were studied by conventional and immunohistochemical techniques. Specimens were distributed as active lesions of cutaneous leishmaniasis (n = 53) (Group I), cicatricial lesions of cutaneous leishmaniasis (n = 35) (Group II) and suggestive scars of healed mucosal leishmaniasis patients (n = 6) (Group II...

background cutaneous leishmaniasis (cl) is an endemic disease in developing countries. although pentamidine orantimonite (glucantime) has been recommended for cutaneous leishmaniasis treatment by the world health organization, there are some concerns too such as high cost, side effects, need for frequent injections, and restricted efficacy. therefore, different methods have been used for cl tre...

background zoonotic cutaneous leishmaniasis (zcl) is polymorphic disease that may show various clinical manifestations. objectives this study investigates the determination of genetic variation within the species of leishmania major isolates from new cases in chabahar, a port city in southeast iran (situated at the iran-pakistan border). migration in this region indicates that leishmaniasis is ...

old world cutaneous leishmaniasis (owcl) usually causes a single, self-healing and uncomplicated lesion mainly on the exposed area of body. this report presents four cases of owcl from iran that misdiagnosed with sarcoidosis, lymphoma, and acne agminata. two out of four patients showed a history of purplish red plaques for at least 5 years who misdiagnosed as sarcoidosis because of histological...

cutaneous leishmaniasis (cl) remains a serious public health concern in kerman province, eastern iran. this study was aimed to conduct a comprehensive review and highlights various aspects of cl in the province of kerman.this article mainly focuses on the studies published in the past 26 years on cl in the province. current data for the present status were obtained through the provincial health...

abstract        background and objective: chabahar is in southern iran located near the iran-pakistan border. since leishmaniasis is an emerging disease in this region, this study aimed to diagnose the disease and identify different species of leishmania parasite in the patients referred to the central laboratory.       methods: this descriptive cross-sectional study was conducted in 2011-2012 ...

Background & Aims: Despite improvements in public health in Iran, cutaneous leishmaniasis has become a growing health issue. About 90% of cutaneous leishmaniasis cases occur in 8 countries including Iran. Kala-azar or visceral leishmaniasis, as an important parasitic disease, is endemic in some areas of Iran. Mapping the distribution of parasitic diseases and determining their relations to geog...

Background: Leishmaniasis is a zoonosis disease. About 350 million people are at risk of developing a disease, with 1.5 to 2 million new cases every year in the world. The aim of this study was to determine the space-time clusters of cutaneous leishmaniasis in north of Khuzestan Province, Iran. Methods: In this cross-sectional study, the annual cutaneous leishmaniasis incidence per 100,000 ind...

The humoral immune response against Leishmania braziliensis histone H1 by patients with cutaneous leishmaniasis is described. For this purpose, the protein was purified as a recombinant protein in a prokaryotic expression system and was assayed by enzyme-linked immunosorbent assay (ELISA) with a collection of sera from patients with cutaneous leishmaniasis and Chagas' disease. The assays showed...