Topical photodynamic therapy (PDT) is a widely used non-invasive treatment for certain non-melanoma skin cancers, permitting treatment of large and multiple lesions with excellent cosmesis. High efficacy is demonstrated for PDT using standardized protocols in non-hyperkeratotic actinic keratoses, Bowen's disease, superficial basal cell carcinomas (BCC) and in certain thin nodular BCC, with supe...

Porokeratosis is a skin disorder clinically characterized by annular plaques with keratotic borders resembling the Great Wall of China and histopathologically by cornoid lamellae. The disease has several clinical variants. Porokeratosis ptychotropica, which has recently become part of these variants, is quite rare and little known. The entity is characterized by verrucous plaques - which may re...

Porokeratosis is a disorder of epidermal keratinization characterized by annular plaques with an atrophic center and hyperkeratotic edges, and includes a heterogeneous group of disorders that are mostly inherited in an autosomal dominant form. This report describes a 5 year-old female patient, with porokeratosis of Mibelli confirmed histopathologically. The rarity of this disorder, its clinical...

Intravesical instillation of Bacillus Calmette-Guerin (BCG) hasbecome an established adjuvant treatment for superficial bladdercarcinoma. This treatment is associated with a relatively high rateof side effects which are mostly reversible spontaneously or canbe treated symptomatically. Serious systemic side effects are lessfrequent. One of rare complications is gran...

Presented herein are 18 cases of erythematous, scaly papules or plaques with microscopic features of both seborrheic keratosis and psoriasis. There was, however, no known clinical diagnosis of psoriasis in any patient, neither at initial presentation nor on follow-up examination. Most lesions were solitary, present for 6-7 months, and identified on the upper or lower extremities. Other sites in...

Purpose Mycobacterium avium complex (MAC) are non-tuberculous mycobacteria that are ubiquitously found in nature and can cause progressive pulmonary disease, superficial lymphadenitis, and disseminated infection in immunocompromised individuals. In this report, we present a case of disseminated MAC cutaneous disease in a patient with mixed connective tissue disease (MCTD) on immunosuppressive t...

A 15-year-old girl underwent allogenic bone marrow transplantation for neuroblastoma. few years later, she noticed a round lesion on her left buttock. Since the had been asymptomatic and never grown, more than 20 passed before saw local doctor to consult about it. Although was suspected be tinea corporis, no fungi were found microscopic examination. Subsequently, administered topical corticoste...

Photodynamic therapy involves the use of light to activate a photosensitizer, localized in the diseased skin, resulting in the formation of cytotoxic reactive oxygen species. Topical photodynamic therapy (PDT) is used to treat nonmelanoma skin cancers, such as actinic keratoses, Bowen's disease, and basal cell carcinoma, superficial as well as nodular. This article presents up-to-date, practica...

Porokeratosis is an abnormal disease of keratinization of epidermis. It is clinically characterized by margins covered with keratin layer and it typically has an atrophied macule with a protruded, circular form. Histopathologically, it shows the findings of cornoid lamella. Risk factors for its development include organ transplantation, long-term use of corticosteroids, immunocompromised status...

Porokeratosis is a rare disease of epidermal keratinization characterized by the histopathological feature of the cornoid lamella, a column of tightly fitted parakeratocytic cells, whose etiology is still unclear. Porokeratosis of Mibelli is a subtype of porokeratosis presenting a single plaque or a small number of plaques of variable size located unilaterally on limbs. It frequently appears in...