PURPOSE To determine the efficacy of intravitreal triamcinolone injections (iv TA) for diffuse persistent diabetic macular oedema (DMO) based on the functional parameter of modification in best corrected visual acuity (BCVA) and the anatomic parameter of quantitative changes in central macular thickness, as determined by optical coherence tomography (OCT). The secondary outcome is to analyse th...

BACKGROUND/AIMS The National Institute for Health and Care Excellence (NICE) has recommended the use of ranibizumab for neovascular age-related macular degeneration (AMD) and for diabetic macular oedema (DMO) as part of its health technology appraisal process. In the economic evaluations of both interventions, utility values were derived from members of the general public wearing contact lenses...

Weak transcranial direct current stimulation (tDCS) induces persisting excitability changes in the human motor cortex. These plastic excitability changes are selectively controlled by the polarity, duration and current strength of stimulation. To reveal the underlying mechanisms of direct current (DC)-induced neuroplasticity, we combined tDCS of the motor cortex with the application of Na(+)-ch...

ABSTRACT We use FIRE-2 zoom cosmological simulations of Milky Way size Galaxy haloes to calculate astrophysical J-factors for dark matter annihilation and indirect detection studies. In addition velocity-independent (s-wave) cross-sections 〈σv〉, we also effective velocity-dependent models, where the cross-section is either p-wave (∝ v2/c2) or d-wave v4/c4). 12 pairs simulations, each run with m...

We present a comprehensive analysis of the shape dark matter (DM) halos in sample 25 Milky Way-like galaxies TNG50 simulation. Using an Enclosed Volume Iterative Method (EVIM), we infer oblate-to-triaxial for DM halo with median $T \simeq 0.24 $. group 3 different categories. Simple (32% population) establish principal axes whose ordering magnitude does not change radius and orientations are al...

While baryonic feedback is one of the most important astrophysical systematics that we need to address in order achieve precision cosmology, few weak lensing studies have directly measured its impact on matter power spectrum. We report measurement parameter with constraints lower and upper limits from cosmic shear. use public data Kilo-Degree Survey VISTA Infrared Galaxy spanning 450 deg$^2$. E...

Introduction: Diabetic macular oedema (DMO) is a major cause of visual loss in the diabetic population. There are several treatment options for DMO, including intravitreal anti-vascular endothelial growth factor (anti-VEGF) injections, which have been shown to improve outcomes. Good compliance regimens associated with greater benefit.
 Purpose: To estimate dropout rates and reasons among D...

This paper presents a machine learning model to predict the effect of Al2O3 nanoparticle content on coefficient thermal expansion in Cu-Al2O3 nanocomposites prepared using an situ chemical technique. The developed is modification Long Short-Term Memory (LSTM) dwarf mongoose optimization (DMO), which mimics behavior DMO find its food for predicting composite. swarm consists three groups, namely ...

Many problems in multi-agent systems can be represented as a Distributed Constraint Optimization Problem (DCOP) where the goal is to find the best assignment to variables in order to minimize the cost. More complex problems including several criteria can be represented as a Multi-Objective Distributed Constraint Optimization Problem (MODCOP) where the goal is to optimize several criteria at the...

[1] Profiles of Mo/total organic carbon (TOC) through the Lower Toarcian black shales of the Cleveland Basin, Yorkshire, United Kingdom, and the Posidonia shale of Germany and Switzerland reveal water mass restriction during the interval from late tenuicostatum Zone times to early bifrons Zone times, times which include that of the putative Early Toarcian oceanic anoxic event. The degree of res...