Bacterial colonization on biomedical devices often leads to biofilms that are recalcitrant antibiotic treatment and the leading cause of hospital-acquired infections. We have invented a novel pretreatment chemistry for device surfaces produce high-density three-dimensional (3-D) network covalently linked S-nitrosothiol (RSNO), which is nitric oxide (NO) donor. Poly(polyethylene glycol-hydroxyl-...

Background: Couples seeking assisted reproductive donation procedures are faced with complex challenges throughout their treatment which can have important psychological impacts on their life. Selecting a suitable donor is one of the hardest decisions they will ever make. This study was carried out to provide an in-depth description of the experiences of couples in relation to donor selection. ...

The objective of the experiment was to determine the effects of fat supplementation on embryo quality of dairy cows and the subsequent success of embryo transfer into recipient heifers fed the same sources of fat. A total of 30 lactating Holstein cows were allotted on d 18 postpartum to 2 groups of 15 donor cows blocked for similar calving dates. Total mixed diets based on silage and fat supple...

BACKGROUND We hypothesized that supplementing a higher mass of renal parenchyma from adult donors, and their younger age, would improve graft function in paediatric recipients. METHODS We calculated estimated glomerular filtration rate (eGFR; Schwartz formula) and absolute glomerular filtration rate (absGFR) in 57 renal-grafted children (1995-2007) aged 3.1-17.9 years, weighing 12.9-85.0 kg, ...

PURPOSE To report our clinical experience and 12-month results of small-incision Descemet-stripping endothelial keratoplasty (DSEK). METHODS Prospective study of 11 eyes of 9 patients who had DSEK. The DSEK technique consisted of stripping the Descemet membrane and endothelium from the recipient cornea. The donor button was prepared by manual dissection and inserted through a 5-mm incision. A...

CONTEXT Iodine is critical for normal thyroid hormone synthesis and brain development during infancy, and preterm infants are particularly vulnerable to the effects of both iodine deficiency and excess. Use of iodine-containing skin antiseptics in intensive care nurseries has declined substantially in recent years, but whether the current dietary iodine intake meets the requirement for hospital...

BACKGROUND The present study explored the process of disclosure in gamete donation families in the UK. METHODS Interviews were conducted with 23 mothers and 15 fathers who had told their 7-year-old child about the nature of their conception. Twelve children were interviewed about what they understood and how they felt about their donor conception (DC). RESULTS The majority of families had d...

OBJECTIVE To review a single-institution 6-year experience with laparoscopic live donor nephrectomy detailing the technical modifications, clinical results, as well as the trends in donor and recipient morbidity. SUMMARY BACKGROUND DATA Since 1995, laparoscopic donor nephrectomy has had a significant impact on the field of renal transplantation, resulting in decreased donor morbidity, without...

AIMS To investigate the role of angiotensin converting enzyme (ACE) (I/D) gene polymorphism in the development of coronary sclerosis after cardiac transplantation. METHODS AND RESULTS Eighty cardiac transplant recipients (44 transplant associated coronary artery disease; 36 non-transplant associated coronary artery disease) and their donors were genotyped by polymerase chain reaction. The all...

Wolbachia are maternally transmitted endocellular bacteria causing a reproductive incompatibility called cytoplasmic incompatibility (CI) in several arthropod species, including Drosophila. CI results in embryonic mortality in incompatible crosses. The only bacterial strain known to infect Drosophila melanogaster (wDm) was transferred from a D. melanogaster isofemale line into uninfected D. sim...