background: understanding of the incident electron energy and angular distributions from clinical electron accelerators (linacs) is important for dosimetry and treatment planning. the most important goals of this study were to evaluate the energy fluence and angular distributions of electron beams from a neptun 10pc linac using the monte carlo (mc) code. materials and methods: the linac electro...

PURPOSE To implement a geometry based particle splitting technique in order to reduce the computation time when generating treatment head phase space files for proton therapy dose calculations using Monte Carlo (MC) calculations and to validate the doses generated from these phase spaces with respect to reference simulations. METHODS The treatment nozzles at the Francis H Burr Proton Therapy ...

The in vivo metabolism and DMA binding of benzo(a)pyrene (BP) was examined in male Sprague-Dawley rat. BP was ad ministered i.v. at dose levels of 1.0 and 10.0 /¿mol/kg. DNA samples from [3H]BP-treated rats were enzymatically digested to deoxyribonucleosides and analyzed by high-pressure liquid chromatography. Several chromatographically distinct nucleoside-bound adducts were observed in lung ...

Atorvastatin, [(R-(R,R)]-2-(4-fluorophenyl)-beta, delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenyl-amino)carbonyl] -1H-pyrrole-1-heptanoic acid calcium salt (CI-981, AT), is a second generation 3-hydroxy-3-methylglutaryl-CoA reductase inhibitor approved for clinical use as a cholesterol lowering agent. The disposition and metabolism of AT, including potential CYP450 induction, was investig...

The detection in urine of recombinant human erythropoietin (rHuEPO), a hormone misused by endurance athletes as a doping agent, is based on the differentiation of its isoelectric pattern from that of the corresponding natural hormone. Different empirical criteria have been proposed for discriminating the images of the patterns but none of them have been elaborated from a rational statistical ap...

Inherent to helical tomotherapy is a dose variation pattern that manifests as a "ripple" (peak-to-trough relative to the average). This ripple is the result of helical beam junctioning, completely unique to helical tomotherapy. Pitch is defined as in helical CT, the couch travel distance for a complete gantry rotation relative to the axial beam width at the axis of rotation. Without scattering ...

Twenty-four-hour systolic blood pressure, diastolic blood pressure, and heart rate profiles were recorded in 17 liver-transplanted patients by noninvaslve ambulatory monitoring and were analyzed with the periodogram method. These recordings were compared with those of control subjects matched for age, sex, and daytime ambulatory blood pressure. Abnormal blood pressure patterns were found in sev...

background: the patterson-parker table was created in 1934 to determine mg-hr required to deliver the prescribed dose to the treatment area. these tables were created using the dosimetric data for 226ra that was determined in air and were utilized for dose calculations around implants with ra-equivalent radionuclides such as 137cs and 192ir. therefore, the differences of the tissue attenuation ...

cadmium, a metal widely used in industrial processes, has been recognized to be a highly toxic and dangerous environmental pollutant. random amplified polymorphic dna (rapd) test is a feasible method to evaluate the toxicity of environmental pollutants on vegetal organisms. herein, two iranian ecotypes of cuminum cyminum (cumin) plantlets following exposure to cadmium (cd) concentrations of 300...

Purpose: In the last years, some studies investigated dosimetric benefits of a free flattening filter for the photon mode in the radiotherapy field. This study aims to provide a theoretical study published and analysis of basic dosimetric properties for a Saturne 43 Linac head to implement free flattening filter beams clinically. Material and Methods: Thi...