Prazosin was administered to 16 patients with essential hypertension in an initial dose of 0.5 mg, after which the blood pressure (BP), pulse, and plasma concentrations of prazosin were measured at 0, 0.5, 1, 1.5, 2, 2.5, 3, 4, 6, 8, and 24 hours. The dose of prazosin was then increased over 16 to 20 weeks, and similar sequences of measurements were obtained twice. Eleven patients completed the...

The majority of quantitative data on the effects of dose-rate come from experiments with cultured cells in vitro. These data are reviewed, and it is concluded that results obtained from the in vitro experience may be carried over, in a quantitative manner, to guide clinical radiotherapeutic design. As an example, there are contradictory guidelines suggested to compensate for changes in dose-rat...

ABSTRACTBackground: as fluoroscopy or different angiographies are usually evaluated using TL dosimeter. Thismethod is a time-consuming procedure therefore, radiologists are usually worried and unawareof their exact radiation dose received during each fluoroscopy or angiography. In this study, anew trend for quick estimation of effective dose based on measuring air-absorbed dose of thescattered ...