نتایج جستجو برای: dqa
تعداد نتایج: 148 فیلتر نتایج به سال:
To gain an understanding of the genomic structure and evolutionary history of the giant panda major histocompatibility complex (MHC) genes, we determined a 636,503-bp nucleotide sequence spanning the MHC class II region. Analysis revealed that the MHC class II region from this rare species contained 26 loci (17 predicted to be expressed), of which 10 are classical class II genes (1 DRA, 2 DRB, ...
FOREWORD This is the 1996 (QA96) version of Guidance for Data Quality Assessment, EPA QA/G-9. The Environmental Protection Agency (EPA) has developed the Data Quality Assessment (DQA) Process as an important tool for project managers and planners to determine whether the type, quantity, and quality of data needed to support Agency decisions has been achieved. This guidance is the culmination of...
The class II antigens ofthe human MHC are cell surface heterodimers composed of noncovalently linked 35-kD a chains and 29-kD (3 chains . These antigens are present on macrophages, B lymphocytes, and other APC (for review, see reference 1). Class II antigens are capable of binding immunogenic peptides and thereby serve as ligand for the TCR (2, 3) . Recent experiments have demonstrated that cla...
Background. The authors conducted a study to validate the following 3 evidence-based, process-of-care quality measures focused on dental caries prevention for children with an elevated Jill Boylston Herndon, PhD; Scott L. Tomar, DMD, MPH, DrPH; Frank A. Catalanotto, DMD; Nancy Rudner, DrPH; I-Chan Huang, PhD; Krishna Aravamudhan, BDS, MS; Elizabeth A. Shenkman, PhD; James J. Crall, DDS, ScD ris...
BACKGROUND The introduction of solid-phase immunoassay (SPI) technology for the detection and characterization of human leukocyte antigen (HLA) antibodies in transplantation while providing greater sensitivity than was obtainable by complement-dependent lymphocytotoxicity (CDC) assays has resulted in a new paradigm with respect to the interpretation of donor-specific antibodies (DSA). Although ...
During recent years, increasing evidence has accumulated that preformed antidonor human leukocyte antigen (HLA) class II antibodies represent significant risk factors for transplant dysfunction and failure (1– 6). Also, the posttransplant development of anticlass II antibodies is associated with a higher incidence of acute and chronic rejection (7–14). In this issue, the report by Issa et al. (...
Cereal Chem. 72(5):475-479 Two different gliadin molecules (designated oc-gliadin and ot/P-gliadin) were synthesized as 52 and 58 ten amino acid (aa) long overlapping peptides for the determination of their B-cell epitopes. Monoclonal antibodies and human serum pools revealed two epitopes common for both gliadins (peptide 14 aa:s 66-75 and peptides 340x aa:s 166-175, 36Wx/p aa:s 176-185) and tw...
Genes of the human leukocyte antigen (HLA)-DR15 haplotype show a strong association with disease risk for multiple sclerosis (MS).Current genotyping tools failed to pinpoint second HLA-DR allele, DRB5*01:01, besides well-known DRB1*15:01 gene, despite their close 100% linkage disequilibrium (LD).Functional studies illustrate complex mechanisms how both DR15 alleles shape CD4+ T cell repertoire ...
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