Motivated by channel measurements in different indoor locations we will show that the WLAN indoor MIMO channel is characterized by few dominant transmission paths mainly corresponding to the LOS path and some strong reflections. In the contrary to the common statistical flat Rayleigh fading channel model we will explain that the WLAN channel is widely deterministic and frequency selective. Furt...

Cytochrome P450 drug metabolizing enzymes are implicated in personalized medicine for two main reasons. First, inter-individual variability in CYP3A4 expression is a confounding factor during cancer treatment. Second, inhibition or induction of CYP3A4 can trigger adverse drug-drug interactions. However, inflammation can downregulate CYP3A4 and other drug metabolizing enzymes and lead to altered...

An advanced multifunctional, hollow metal-organic framework (MOF) drug delivery system with a high drug loading level and targeted delivery was designed and fabricated for the first time and applied to inhibit tumour cell growth. This hollow MOF targeting drug delivery system was prepared via a simple post-synthetic surface modification procedure, starting from hollow ZIF-8 successfully obtaine...

bioactive products from snail slime of “helix” specie have potential applications in preventing and/or treating several human diseases and in cancer diagnosis. however, the poor pharmacokinetics characteristics of these natural compounds limit their use. nanotechnology offers promising solutions for the enhanced formulation of these molecules through the synthesis of nanosized drug delivery sys...

BACKGROUND The increasing prevalence of drug-resistant tuberculosis and the threat of extensively-drug-resistant tuberculosis in HIV hotspots have made the detection and treatment of drug-resistant tuberculosis in the sub-Saharan Africa setting a global public health priority. OBJECTIVE We sought to examine the impact and challenges of tuberculosis diagnostic capacity development for the dete...

We exhibit a possible road towards a strong converse for the quantum capacity of degradable channels. In particular, we show that all degradable channels obey what we call a “pretty strong” converse: When the code rate increases above the quantum capacity, the fidelity makes a discontinuous jump from 1 to at most 1 √ 2 , asymptotically. A similar result can be shown for the private (classical) ...

Drug delivery researches has drawn tons of attention to achieve the targeted therapies that work for many diseases. Nanogels, a type polymeric hydrogels with nanoscale size, are promising materials drug applications. However, current polymers used synthesizing nanogels lack in biocompatibility, stability, and low biosafety. This review focus on mannan-based high loading capacity, multifunctiona...

Smart Anticancer Drug Nanocarriers In article number 2206813, Neralla Vijayakameswara Rao, Wei-Hung Chiang, and co-workers develop a plasma engineering of nitrogen-doped graphene quantum dot (NGQD) hydrogels with robust, porous photoluminescence properties. The presence NGQDs in the hydrogel can accelerate improve loading capacity anticancer drug doxorubicin via π-π interaction, exhibits stable...

Individual variability in reward-based learning has been ascribed to quantitative variation in baseline levels of striatal dopamine. However, direct evidence for this pervasive hypothesis has hitherto been unavailable. We demonstrate that individual differences in reward-based reversal learning reflect variation in baseline striatal dopamine synthesis capacity, as measured with neurochemical po...

Berberine was loaded in yeast cells of Saccharomyces cerevisiaeas a novel pharmaceutical carrier to improve the treatment ofmany diseases. The yeast-encapsulated active materialsshowedhigh stability and bioavailability due to the enhanced solubility and sustained releasing. In this study, different characteristics of prepared berberine loaded yeast cells (loading capacity, release kinetic order...