نتایج جستجو برای: drug treatments
تعداد نتایج: 743487 فیلتر نتایج به سال:
Although corticosteroids and immunosuppressants are widely used for the treatments of various autoimmune diseases such as systemic lupus erythematosus (SLE), we often experience patients with SLE who are resistant to these treatments. P-glycoprotein (P-gp) of membrane transporters, a product of the multiple drug resistance (MDR)-1 gene, is known to play a pivotal role in the acquisition of drug...
Alzheimer's Disease (AD) is the most common cause of dementia, affecting approximately two thirds of the 35 million people worldwide with the condition. Despite this, effective treatments are lacking, and there are no drugs that elicit disease modifying effects to improve outcome. There is an urgent need to develop and evaluate more effective pharmacological treatments. Drug repositioning offer...
addiction to drugs, such as heroin, cocaine and alcohol, exacts great human and financial costs on society. various evidence-based pharmacological and psychosocial interventions are currently used in the treatment of drug addiction but they do not produce adequate therapeutic benefits in every patient. further, barriers such as financial cost, lack of availability, or perceptions of existing tr...
The kinetics of the time-dependent antitumor effects of paclitaxel are not fully understood; some literature reports indicate a higher activity by prolonging treatment durations, whereas other reports indicate no enhancement under in vitro conditions. The present study was designed to address this controversy and to determine the mechanism of the higher cytotoxicity associated with longer treat...
The holy grail of healthcare financing is a system that insures access to health care of appropriate intensity that is provided as e ciently as possible so as to control the growth of overall expenditure. Global budgeting systems can e↵ectively control the growth of overall expenditures by setting a cap on total reimbursements to providers. However, the e↵ect on the intensity or e ciency of car...
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