Strongyloidiasis is a common disease worldwide, has complex life cycle and infect humans percutaneously. We report case of 46-year-old woman, presented with complaints abdominal pain, distension. She was on PPI (Proton Pump Inhibitors) for recurrent gastritis. also gives history steroid intake joint pain. USG abdomen showed moderate ascites. Upper GI endoscopy diffuse erythematous gastric mucos...

Ectopic opening of the pancreatic and bile ducts (EOPBD) into the duodenal bulb is an extremely rare congenital anomaly with unknown clinical implications. We presented a case of gallbladder cancer with EOPBD into the duodenal bulb. A 57-year-old male was referred to our hospital with intermittent right upper abdominal pain. Endoscopic retrograde cholangiopancreatography and magnetic resonance ...

Cronkhite-Canada syndrome (CCS) is known to have a malignant potential (1); this is the first report of adenocarcinoma arising from the major duodenal papilla of a patient with CCS. The patient was a 66-year-old Japanese man who had been suffering from cacogeusia, alopecia, onychodystrophy and cutaneous hyperpigmentation for 2 years was referred to our hospital. Esophagogastroduodenoscopy and c...

Strongyloidiasis is a common parasitic disease in tropical regions of the world. Infection with Strongyloides stercoralis usually remains asymptomatic with peripheral eosinophilia and uncontrolled growth. Consequently, immunocompromised individuals are at a higher risk of complications of this disease. We present a case of an immunocompetent patient whose complaint of acute abdominal pain was f...

A 50-year-old female became aware of skin yellowing and consulted another hospital where she was diagnosed intraoperatively with duodenal cancer because of lymph node metastases around the aorta. Endoscopy revealed type IIa + IIc cancer distal to the duodenal papilla, and biopsy allowed a diagnosis of well-differentiated adenocarcinoma. Computed tomography revealed a large number of lymph node ...

OBJECTIVE To study the frequency of positive serology for celiac disease (CD) in patients with duodenal biopsies suggestive of this disease. MATERIAL AND METHODS Cross sectional study. We included patients with duodenal biopsies histologically compatible with CD and antigliadin, antiendomysial and IgA antitransglutaminase antibodies. We defined a "case" of CD if there was a positive biopsy an...

Background and Aim. Chromogranin A (CgA) is a common marker for endocrine cells. The density of duodenal CgA cells is reduced in patients with irritable bowel syndrome (IBS). Methods. The present study was undertaken to evaluate the density of duodenal CgA as a biomarker for the diagnosis of IBS. Two hundred and three patients with IBS were recruited (180 females and 23 males; mean age, 36 year...

Many growth factor receptors including the epidermal growth factor receptor function through tyrosine kinase activity. The aim of this study was to examine the constitutive level of tyrosine phosphorylation in the normal duodenum and in the hyperproliferative coeliac duodenum. A flow cytometric assay was devised using monoclonal antibody to phosphorylated (but not native) tyrosine residues to d...

A 43 year-old woman, with long standing rheumatoid arthritis treated with metotrexate, presented due to diarrhea/mucorrea without rectal bleeding associated to marked weight loss of 4 months duration. Physical examination was normal. Laboratory work-up revealed iron deficiency anemia (haemoglobin 9,2 g/dL, ferritin 2 ng/mL) with serum tumor markers in normal range. Colonoscopy with ileal and co...

A gastrointestinal explant culture system was developed and compared to the mononuclear cell extraction and enzyme-linked immunospot assay method for measurement of immunoglobulin A (IgA) and IgG antibody-secreting cells (ASCs) in gastric antral and duodenal biopsies of non-Helicobacter pylori-infected volunteers. IgA and IgG were detected in explant supernatants during 6 to 7 days of culture i...