The cycle length dependence of the action potential duration and the effective refractory period of the right ventricular endocardium were investigated in 24 patients undergoing electrophysiologic studies for suspected ventricular tachycardia. The action potential duration at 90% repolarization and the effective refractory period at twice diastolic threshold strength were measured at the same c...

background & objective: outpatient surgery can be performed by general or spinal anesthesia. spinal anesthetic drugs have side effects. many anesthesiologists choose general anesthesia, because of its relative predictability and to avoid undesirable side effects associated with spinal anesthesia. for example lidocaine is frequently associated with transient neuroligic symptoms (tns). bupivacain...

Stretch-activated channels (SACs) have been considered as one of the possible modulators on the mechanisms of mechano-electrical feedback (MEF) in the heart. With the abilities to modulate action potential duration (APD) during the systolic period and to trigger action potentials directly by diastolic stretch, SACs could play an important role on stretch-induced arrhythmias. The objective of th...

mucosa-adhesive gels can be used as a useful mean of delivering drugs to or via mucosal membranes, and in particular buccal mucosa. carbomers are among the best mucosa-adhesive materials known. the aim of this study was to compare the results obtained from the mucosa-adhesive strength of aqueous gels containing carbomers, either alone or in combination, to the data obtained from assessing the d...

background & aim: the plants of the greenhouse have been affected by infestation of the pest trialeurodes vaporariorum, called greenhouse whitefly, which markedly reduced production. synthetic insecticides have been widely developed and, their extensive use has brought about disadvantages, like environmental disturbance, pest resistance, lethal effects on non target organisms and toxicity t...