Agrowing body of evidence suggests that endothelial dysfunction is associated with cardiovascular events. Endothelial dysfunction can be regarded as a syndrome that exhibits systemic manifestations associated with significant morbidity and mortality. The concept of endothelial dysfunction should be extended beyond the conduit vessels into the vascular wall and even to the bone marrow and the pr...

Diastolic dysfunction, often seen with increasing age, is associated with reduced exercise capacity and increased mortality. Mortality rates in older individuals are linked to the development of disability, which may be preceded by functional limitations. The goal of this study was to identify which echocardiographic measures of diastolic function correlate with physical function in older subje...

Multiple organ dysfunction syndrome (MODS), defined as the presence of altered organ function in an acutely ill patient such that homeostasis cannot be maintained without intervention, is a cause of high morbidity and mortality in humans and animals. Many advances have been made in understanding the pathophysiology and treatment of this syndrome in human medicine, but much still is unknown. Thi...

The relation between dyspnoea of presumed cardiac origin and disturbed left ventricular systolic function was studied in a group of 67 year old men from the general population of Gothenburg, Sweden. Forty two men with cardiac dyspnoea were identified and 45 controls were randomly selected from a screened cohort of 644 men. Dyspnoea was graded according to the World Health Organisation standard,...

abstract   background: sacroiliac joint (sij) dysfunction is a widely known but poorly defined   cause of low back pain. to our knowledge, few published studies have been   conducted to evaluate systematically the prevalence and significance of concomitant   sacroiliac joint dysfunction in patients with herniated lumbar discs. as concomitant   sij dysfunction in low back pain patients is likely...

abstract   background: sacroiliac joint (sij) dysfunction is a widely known but poorly defined cause of low back pain. to our knowledge, few published studies have been conducted to evaluate systematically the prevalence and significance of concomitant sacroiliac joint dysfunction in patients with herniated lumbar discs. as concomitant sij dysfunction in low back pain patients is likely to resp...

Abhinay Reddy Koppula, Dudekonda Sai Sandeep and Tekuru Yogesh Hepatic Encephalopathy (H.E), defined as a spectrum of neuropsychiatric abnormalities in patients with severe liver dysfunction. It is most common complication advanced disease significant incidence death rate [1].

Aim: Obesity is a risk factor for sexual dysfunction. The aim of this study was to determine the frequency dysfunction in patients diagnosed with morbid obesity.Methods: patient group included consisted 78 morbidly obese BMI≥40 kg/m2 and 68 healthy individuals normal BMI. data were obtained by using sociodemographic information form filled participants, Beck anxiety scale, depression scale Golo...

Heart failure frequently involves diastolic dysfunction that is characterized by a prolonged relaxation. This prolonged relaxation is typically the result of a decreased rate of intracellular Ca(2+) sequestration. No effective treatment for this decreased Ca(2+) sequestration rate currently exists. As an approach to possibly correct diastolic dysfunction, we hypothesized that expression of the ...

BACKGROUND In this retrospective analysis we investigated the predictive performance of orthostatic hypotension (OH) and ambulatory blood pressure monitoring (ABP) to predict autonomic dysfunction. METHODS Statistical associations among the candidate variables were investigated and comparisons of predictive performances were performed using Receiver Operating Characteristics (ROC) curves. R...