Breast cancer still imposes a significant health burden on women worldwide. As is true with most other cancer diseases, early diagnosis and implementation of prompt treatment are crucial in battling this disease. Biological markers from blood, urine, and tissue can signal predisposition, onset, response to drug treatment, and recurrence of breast cancer. Thus discovery and early detection of bi...

inflammatory myopathy is a paraneoplastic syndrome. inflammatory myopathy may be the first manifestation of underlying malignancy. it was reported in patients with colon cancer, breast cancer, ovarian cancer, lung cancer and non-hodgkin lymphoma. there are few reports regarding inflammatory myopathy in patients with gastric cancer. we want to present inflammatory myopathy as early manifestation...

the present research is a field study in order to investigate scale and ways of doing breast self examination (bse). 270 nurses employed by the medical sciences university’s hospitals related to the ministry of health, and medical education in city of tehran are selected and involved in research on the basis of simple random sampling. the data collection tool was a protrayed questionnaire which...

To the Editor : Women carrying a highly penetrant mutation in the genes BRCA1 (breast cancer 1) or BRCA2 have a 60–85% lifetime risk of breast cancer and a 15–40% lifetime risk of ovarian cancer (1). In Asia, the contribution of BRCA1/2 to breast cancer and the ethnic distribution of the different type of mutations remain relatively unexplored. We performed BRCA1/2 mutation screening using high...

PURPOSE The lower breast cancer incidence in Asian populations compared with Western populations has been speculated to be caused by environmental and genetic variation. Early-onset breast cancer occupies a considerable proportion of breast cancers in Asian populations, but the reason for this is unclear. We aimed to examine miRNA expression profiles in different age-onset groups and pathologic...

BACKGROUND Chemotherapy-induced amenorrhea (CIA) is one of the most frequent therapy-related adverse events observed in breast cancer patients who have undergone chemotherapy. Although the characteristics of CIA have been studied in Western countries, little is known about CIA in Asian. We conducted a retrospective analysis to assess the characteristics and influencing factors of CIA and its as...

background: an early diagnosis of breast cancer relates directly to an accurate treatment plan and strategy. early detection of breast cancer before its development would be a significant reduction of morbidity and mortality rates. the aim of this preliminary study is to investigate the sensitivity of wide angle x-ray diffraction (waxrd) method on women hair samples of healthy and breast cancer...

The aims of our study were: (1) to detect disease-associated BRCA1 mutations in a series of Portuguese patients with breast and/or ovarian cancer; (2) to evaluate the expression of molecular markers of biological behaviour, namely ER, proliferative index, c-erb-B2, p53, sialyl-Tn and angiogenic index in a series of hereditary breast cancer (HBC) in relation to sporadic cases. We selected 65 pat...