BACKGROUND Salivary matrix metalloproteinase (MMP)-8 is currently considered to be one of the most promising biomarkers for early diagnosis of periodontitis, however, several recent studies showed conflicting results. OBJECTIVE To determine the salivary matrix metalloproteinase (MMP)-8 levels between periodontitis patients and healthy individuals, and to assess its diagnostic value in periodo...

although periodontitis is a chronic inflammatory disease but some factors of acute inflammation phase are involved in this disease among which is the c-reactive protein (crp). to minimize its effects, anti-inflammatory drugs or non-pharmacological approaches such as oral hygiene is recommended. crp can also be used for the prediction and early detection of periodontal disease. the aim of the pr...

Abstract The oral cavity is a unique stricture; it combines mucosal and bone tissue microenvironments with their respective immunological responses. In fact, inflammation leads to destruction in the prevalent human disease, periodontitis. periodontitis, immune cells, particular Th17 neutrophil mediated responses have been linked pathogenesis, however not yet understood how stromal microenvironm...

Aggressive periodontitis is a rare, severe and rapidly progressing periodontal disease. Early diagnosis is of utmost importance for establishing treatment in order to stop periodontal destruction and prevent tooth loss. The aim of this study is to describe the occurrence of aggressive periodontitis in patients at a Dental School in Brazil by means of a cross-sectional study. First, records from...

Periodontitis is characterized by the loss of the supporting tissues of the teeth in an inflammatory-infectious context. The diagnosis relies on clinical and X-ray examination. Unfortunately, clinical signs of tissue destruction occur late in the disease progression. Therefore, it is mandatory to identify reliable biomarkers to facilitate a better and earlier management of this disease. To this...

Background: Chronic Periodontitis is the most frequently occurring form of periodontal diseases. Progression of the chronic periodontitis might lead to both esthetic and functional impairment. Early diagnosis and treatment will prevent its progression. Salivary biomarkers such as arginase activity estimation will be of help for assessing the present periodontal status. In the present study, sal...

Background Periodontitis and osteoporosis are two diseases found worldwide and increase in intensity with increasing age of the patients. The severity of osteoporosis and periodontitis are found to be more in women during menopause. The aim of this study was to assess and correlate osteoporosis and periodontal disease among post-menopausal women. Materials and Methods The study consisted of 9...