In order to study left ventricular diastolic function in diabetes mellitus, simultaneous echo- and phonocardiograms were recorded in 142 diabetics (free from heart disease), 20 normal subjects, and 16 patients with coronary artery disease. The resultant traces were digitised, and left ventricular relaxation and the rate and duration of cavity dimension increase and wall thinning were determined...

Background Caloric restriction increases plasma non-esterified fatty acid (NEFA) levels, and increases myocardial triglyceride content. It has been shown that elevated levels of NEFA’s in patients with metabolic disease (metabolic syndrome/ type 2 diabetes mellitus) are associated with a decrease in left ventricular function. However little is known about its effects on right ventricular functi...

We have shown a close relation between clinical microvascular complications and abnormalities of left ventricular function in 185 established diabetics without clinical heart disease. In 50 insulin-dependent diabetics who presented at under 20 years of age there was a correlation between the duration of diabetes and the isovolumic relaxation time, minimal dimension to mitral valve opening, and ...

Background: Infants of Diabetic Mothers (IDMs) are at known risk for the development hypertrophic cardiomyopathy (HCM). Echocardiography is essential diagnosis HCM, to assess left ventricular function, and degree ventricle obstruction, rule out structural cardiac malformations.
 Objective: To study association maternal third-trimester glycemic level with HCM in IDMs.
 Study Design: Ob...

BACKGROUND The leptin receptor-deficient db/db mouse is a well-established type II diabetes animal model used to investigate diabetic cardiomyopathy. Previous reports have documented diabetic cardiomyopathy is accompanied by cardiac structural and functional abnormalities. To better elucidate early or subtle changes in cardiac performance in db/db mice, we used speckle tracking echocardiography...

normal 0 false false false en-us x-none ar-sa microsoftinternetexplorer4 background : supervised exercise-based cardiac rehabilitation programs (crp) have been suggested to all patients, especially after myocardial infarction. however, the effects of cardiac rehabilitation on systolic function are controversial. the aim of this study was to examine the effects of an 8-week cardiac rehabilitatio...

OBJECTIVE Type 2 diabetes is associated with left ventricular hypertrophy (LVH) and diastolic dysfunction, which may eventually lead to clinical heart failure. We sought to determine the cardiovascular effects of adolescent-onset type 2 diabetes. RESEARCH DESIGN AND METHODS We recruited diabetic girls (8 with type 2 and 11 with type 1 diabetes) from a hospital diabetes service and nondiabetic...

introduction:  in patients who underwent surgery to repair tetralogy of fallot, right ventricular dilation from pulmonary regurgitation may be result in right ventricular failure, arrhythmias and cardiac arrest. hence, pulmonary valve replacement may be necessary to reduce right ventricular volume overload. the aim of present study was to assess the effects of pulmonary valve replacement on rig...