Pre-eclampsia continues to be one of the major causes of maternal mortality. ~ Anaesthetic considerations in preeclampsia are important and may contribute to the overall management. 2 Pre-eclampsia is characterized by the triad of (1) hypertension, (2) proteinuria and (3) oedema. 3 Hypertension in pregnancy is usually associated with pre-eetampsia but can also be due to other hypertensive disor...

Eclampsia is said to occur when a woman with preeclampsia experiences generalised tonic-clonic seizures during pregnancy or shortly after delivery [1]. Eclampsia complicates between 1 to 2% of all cases of severe preeclampsia [2]. Preeclampsia is a multi-systemic disorder, characterised by hypertension and proteinuria occurring after the 20th week of pregnancy in a woman who has been previously...

Eclampsia is said to occur when a woman with preeclampsia experiences generalised tonic-clonic seizures during pregnancy or shortly after delivery [1]. Eclampsia complicates between 1 to 2% of all cases of severe preeclampsia [2]. Preeclampsia is a multi-systemic disorder, characterised by hypertension and proteinuria occurring after the 20th week of pregnancy in a woman who has been previously...

Background: Lactate Dehydrogenase (LDH) is most often measured to evaluate tissue damage. Magnesium sulfate is used for seizure therapy and as prophylaxis for eclampsia and preeclampsia, worldwide. The objectives were: 1. To assess serum LDH levels as a biochemical marker to reflect the severity of pre-eclampsia/eclampsia 2. To study the alterations in serum magnesium levels in eclampsia patien...

The mainstay of the management of severe pre-eclampsia is early referral, stabilization of the mother with antihypertensive therapy and anticonvulsants if required, full assessment of the mother and the baby, and delivery on the best day in the best way. It is to be remembered that delivery is the long-term cure, but most women get worse after delivery and most maternal deaths occur postpartum....

In the 1950s and 1960s, researchers Leon Chesley, John Annitto, and Robert Cosgrove investigated the possible familial factor for the conditions of preeclampsia and eclampsia in pregnant women. Preeclampsia and eclampsia, which are related to high blood pressure, have unknown causes and affect at least five percent of all pregnancies. The researchers, who worked at Margaret Hague Maternity Hosp...

Vascular endothelial growth factor (VEGF) plays a crucial role in physiological vasculogenesis and vascular permeability and has been implicated in the pathogenesis of pre-eclampsia. Our present study was undertaken to identify associations between three functional VEGF gene polymorphisms, linked with altered VEGF gene responsiveness, and pre-eclampsia. The study involved 42 pre-eclamptic and 7...

“Posterior reversible encephalopathy syndrome (PRES)” is a clinico radiological entity, the characteristic neuro-imaging features and non-specific symptoms including headache, confusion, visual disturbances and seizures. Vasogenic edema, which is the most probable underlying pathology results in detectable Parieto-occipital white matter changes in imaging. Vasogenic edematous changes of PRES ar...

Eclampsia continues to be one of the leading causes of Maternal morbidity and mortality in developing countries. It is true that with the outreach of Governments and Non Government agencies, more women are able to access antenatal care. This has increased the scope of early detection of cases of hypertension during pregnancy and thereby preventing development of eclampsia. However, with the deg...

In the present study, we studied the influence of serum high-molecular weight adiponectin (HMWA) levels in patients with pregnancy-induced hypertension (PIH) on the occurrence of eclampsia in secondary pregnancy and its related mechanisms. In total, 130 patients who were diagnosed with PIH for the first time were selected for this study; the median interval of the secondary pregnancy was 28.5 m...