Metastatic breast cancer is the second leading cause of cancer-related deaths among women. Triple-negative breast cancer (TNBC) is a highly aggressive subcategory of breast cancer and currently lacks well-defined molecular targets for effective targeted therapies. Disease relapse, metastasis, and drug resistance render standard chemotherapy ineffective in the treatment of TNBC. Because previous...

BACKGROUND High levels of exhaled carbon monoxide (eCO) are a marker of airway or lung inflammation. We investigated whether hypo- or hyperventilation can affect measured values. METHODS Ten healthy volunteers were trained to achieve sustained end-tidal CO2 (etCO(2)) concentrations of 30 (hyperventilation), 40 (normoventilation), and 50 mmHg (hypoventilation). As soon as target etCO(2) values...

Eco-driving is a driving style that can significantly reduce fuel consumption and CO2 emission. Current methods for eco-driving practice are inefficient or not easily accessible. Therefore, we introduce iCO2, an online multi-user three-dimensional (3D) ecodriving training space, which was developed in Unity3D and made available as a Facebook application since September 2012. In iCO2, agents are...

Number: 007-0582 Abstract Title: A Closed-loop Supply Chain Model for Managing Overall Optimization of Eco-efficiencyTitle: A Closed-loop Supply Chain Model for Managing Overall Optimization of Eco-efficiency Authors: Name: Wei D. Solvang, Ziqiong Deng, Bjoern Solvang Organization: Department of Industrial Engineering, Narvik University College, Norway Address: Lodve Langes gate 2, pb. 385, N-8...

Ecological security is an important basis of the entire human security system, the cornerstone for human survival. Knowing the status of ecological security is crucial for making decisions to avoid ecological disaster. Existing research, both the basic research on ecological security mechanism and information service systems, is still primitive in their abilities to resolve eco-security problem...

Heritable trait variation is a central and necessary ingredient of evolution. Trait variation also directly affects ecological processes, generating a clear link between evolutionary and ecological dynamics. Despite the changes in variation that occur through selection, drift, mutation, and recombination, current eco-evolutionary models usually fail to track how variation changes through time. ...

As an emerging field of eco-efficiency, tourism eco-efficiency is becoming an important way to measure the sustainable development of tourism. This study calculated and decomposed tourism CO2 emissions in China, explored its evolution and distribution characteristics by using the ratio method of tourism eco-efficiency, and analyzed the influencing factors by adopting a regression model. The res...

We propose ECO: a new way to generate embeddings for phrases that is Efficient, Compositional, and Order-sensitive. Our method creates decompositional embeddings for words offline and combines them to create new embeddings for phrases in real time. Unlike other approaches, ECO can create embeddings for phrases not seen during training. We evaluate ECO on supervised and unsupervised tasks and de...