in the united states schools in the k12 school system, that provide education for primary, junior and senior high school students, are moving toward information systems to solve and automate some manual processes performed in these schools. with this movement, and the pressure on schools to use technology to improve student achievement, many schools are turning to learning management systems as...

Uropathogenic organisms have evolved numerous defense mechanisms against antimicrobial agents, hence resistance to old and newly available drugs are increasing at an unprecedented level. The events of antibiotic resistance have lead for screening of several medicinal plants for their potential antimicrobial activity. The aim of this study was to evaluate the antimicrobial efficacy of Cyminumcum...

The Bacterial Foraging Optimization (BFO) is one of the metaheuristics algorithms that most widely used to solve optimization problems. The BFO is imitated from the behavior of the foraging bacteria group such as Ecoli. The main aim of algorithm is to eliminate those bacteria that have weak foraging methods and maintaining those bacteria that have strong foraging methods. In this extent, each b...

Most inverse classification algorithms address discrete attributes and can not deal with quantitative attributes. In order to overcome the disadvantage, the discretization algorithms are applied to the inverse classification algorithms, and the main idea is: firstly, a group of feature attributes are selected by using feature selection algorithm; then, the quantitative attributes are discretize...

The primary technique currently used to detect biological agents is based on immunoassays. Although sensitive and specific, currently employed immunoassays generally rely on the detection of a single epitope, and therefore often cannot discriminate subtle strain-specific differences. Since DNA microarrays can hybridize hundreds to thousands of genomic targets simultaneously and do not rely on p...

BACKGROUND Kaposi sarcoma-associated herpesvirus (KSHV) encodes 12 pre-microRNAs that yield 25 mature microRNAs. We previously reported phylogenetic analysis of the microRNA-coding region of KSHV from Kaposi sarcoma (KS), primary effusion lymphoma (PEL), and multicentric Castleman disease (MCD) patients. We observed a high level of conservation for most sequences but also a divergent cluster of...

Small volume operation and rapid thermal cycling have been subjects of numerous reports in micro reactor chip development. Sensitivity aspects of the micro PCR reactor have not been studied in detail, however, despite the fact that detection of rare targets or trace genomic material from clinical and/or environmental samples has been a great challenge for microfluidic devices. In this study, a ...

Domestic cats share human living environments and genetic traits. They develop spontaneous feline mammary carcinoma (FMC) with similar histopathology to human breast cancer. HER2 and AKT phosphorylation was demonstrated in primary FMC by immunoblot analysis, indicating HER2 as a therapeutic target. FMC lines K12 and K248 expressing HER1, HER2, and HER3 were sensitive to receptor tyrosine kinase...