BACKGROUND & AIMS Most reports on eosinophilic esophagitis (EE) are limited to small series from single institutions. This study describes features of EE in a broader population. METHODS A national pathology database (Caris Diagnostics, Irving, TX) was used to identify EE cases from a cohort of upper endoscopies. Slides from potential cases were reviewed by pathologists. Study inclusion requi...

Jiedu Xiaozheng Yin decoction (JXY) is a type of Chinese traditional medicine, which has been used to treat various types of cancer. The present study explored the mechanisms underlying the anticancer activity of JXY. The effects of ethyl acetate extraction of JXY (EE-JXY) were evaluated on the HepG2 human hepatoma cell line in vitro and in vivo. Following treatment of the HepG2 cells with EE-J...

The Wiedemann-Franz law, connecting the electronic thermal conductivity to the electrical conductivity of a disordered metal, is generally found to be well satisfied even when electron-electron (e-e) interactions are strong. In ultraclean conductors in the hydrodynamic regime, however, large deviations from the standard form of the law are expected, due to the fact that e-e interactions affect ...

The 4-hydroxyacetophenone monooxygenase (HAPMO) from Pseudomonas fluorescens ACB catalyzes NADPH- and oxygen-dependent Baeyer-Villiger oxidation of 4-hydroxyacetophenone to the corresponding acetate ester. Using the purified enzyme from recombinant Escherichia coli, we found that a broad range of carbonylic compounds that are structurally more or less similar to 4-hydroxyacetophenone are also s...

objective(s): we examined the effects of endurance exercise in the presence of bunium persicum extract administration on lipid profile and cardiorespiratory capacity in hypercholesterolemic male mice. materials and methods: forty male hypercholesterolemic mice were divided into four groups: vehicle, endurance exercise (ee), bunium persicum extract (bpe), and ee + bpe. the exercise protocol was ...

objective: this study was designed to examine the effect of environmental enrichment during methamphetamine (meth) dependency and withdrawal on methamphetamine-induced spatial learning and memory deficits and obsessive-compulsive behavior. method: adult male wistar rats (200 ± 10 g) chronically received bi-daily doses of meth (2 mg/kg, sc, with 12 hours intervals) for 14 days. rats reared in st...

Eosinophilic esophagitis (EE) is a clinical entity characterized by eosinophilic infi ltration limited to the esophageal epithelium without signifi cant eosinophilic infl ammation of the remainder of the upper gastrointestinal tract mucosa. It can occur in isolation or as part of an atopic spectrum together with asthma, allergic rhinitis and/or atopic dermatitis. EE was fi rst described in the ...

Acute lung injury (ALI) is a life threatening condition associated with hypoxemia, diffuse alveolar damage, inflammation, and loss of lung function. Lipopolysaccharide (LPS; endotoxin) from the outer membrane of Gram-negative bacteria is a major virulence factor involved in the development of ALI. The depletion of glutathione (GSH), an essential intra- and extra-cellular protective antioxidant,...